Glioblastoma multiforme (GBM) is the most common and the most aggressive type of brain cancer; the median survival time from the time of diagnosis is approximately one year. GBM is characterized by the hallmarks of rapid proliferation and aggressive invasion. miR-451 is known to play a key role in glioblastoma by modulating the balance of active proliferation and invasion in response to metabol...

with the collapse of soviet :union:, central asian countries came into independence. the countries were neglected by russia during the first years after their formation. this encouraged other regional and trans-regional powers to interfere in the region and try to maximize their interests. shifting its foreign-policy process, russia kept its eyes on look-east policy and tried to prevent others ...

Collective cell migration is a mode of movement crucial for morphogenesis and cancer metastasis. However, little is known about how migratory cells coordinate collectively. Here we show that mutual cell-cell attraction (named here coattraction) is required to maintain cohesive clusters of migrating mesenchymal cells. Coattraction can counterbalance the natural tendency of cells to disperse via ...

mutual funds are the best tool to mobilize savings and investments in an economy and pakistan is the pioneer in south asia, but this industry is not as much mature in comparison to its age in pakistan. this paper examines the performance of closed ended mutual funds in pakistan by using five different ranking measures during a period of january 2009 to december 2013 and the sample consists of o...

Turkey has been exposed to constant migration flows in the historical process, and Anatolia shaped as a geography. The civil war Syria 2011 became turning point Turkey. Turkish social welfare regime, which mostly covers immigrants from Europe, reshaped after influx of Syrian refugees. This study deals with impact change regime on movements towards On other hand, effect opportunity areas labor m...

The purpose of this study is to investigate collective dynamics coupled communities that evolve according the population game «Battle Sexes». A separate community includes two interacting populations players opposite sex, where each player has one possible competing behavior strategies. It necessary determine possibility mutual synchronization oscillations in number adhering a particular strate...

umbilical and supraumbilical catheter insertion is a common procedure performed in the nicu. it is a safe and usually easy procedure devoid of serious mishaps, morbidity and mortality. complications such as hemorrhage, infection, hernia, evisceration, omphalitis, portal vein thrombosis and portal hypertension may occur after umbilical catheter insertion. other uncommon and rare complications re...

introduction accidents are the second leading cause of disabilities; a problem that causes physical and psychological disorders, and in more severe cases, death. the risks should be identified to suggest the best way to confront and eliminate them. therefore, this study reviews the prevalence and types of accidents among ethnic nomads. materials and methods the current research is a descriptive...