Esophageal squamous cell carcinoma (ESCC) is an aggressive tumor that is typically diagnosed only when the tumor has gained remarkable size, extended to peripheral tissues, and led to dysphagia. Five-year survival of advanced cancer is still very poor (19%), even with improved surgical techniques and adjuvant chemoradiation therapy. Therefore, early detection and prevention are the most importa...

This study evaluated the criteria for quality of life (QoL) using standardized short-form health survey with only 36 questions (SF-36; Version 2.0) and Consumer Product Safety Commission (CPSC) questionnaires to study the relationship between QoL and living conditions of seniors in Golestan province in Iran. This was an analytical cross-sectional study with descriptive and analytical parts. The...

UNLABELLED Background Several studies have examined the effects of folic acid fortification on the occurrence of orofacial clefts. This study was carried out to evaluate the impact of flour fortification with folic acid on oral clefts in Northern Iran. METHODS In this hospital based study from March 2006 to September 2009, we screened the total number of live births at all hospitals in Golest...

OBJECTIVE The present study aimed to determine the effect of reminiscence on cognitive status and memory of a sample of elderly people who lived in aged day centers in Golestan province, Iran. METHODS This study was a semi-experimental research. The subjects consisted of 45 elderly people who referred to the aged day centers of Golestan province. Each four groups of 45 aged subjects (4 groups...

BACKGROUND Aflatoxins are the most common mycotoxins that contaminate crops. They are produced by fungi such as Aspergillus flavus and Aspergillus parasiticus. Wheat (Tricitumaestivum) is one of the most important staple foods used in Iran, and the environmental conditions in the north of Iran are favorable to fungal growth. This study was designed in order to determine the aflatoxin concentrat...

Introduction: More than 350 million people are chronic carriers of HBV and many of them develop progressive diseases, including cirrhosis and hepatocellular carcinoma. Many of those infected develop persistent disease and a proportion goes on to develop liver failure and cancer. Researchers showed that double mutations of the x gene at position 1762 and 1764, have been found in chronic hepatiti...

BACKGROUND One of the main and basic pillars of health system promotion is the equitable distribution of health facilities in order to ensure fair access of people in the community to the health services. The goal of this study was to classify the health structural indicators in Golestan Province using Scalogram analysis model. METHOD A descriptive study was conducted in 2010. Data related to...

We evaluated the effect of NQO1 genetic variation on PAH-DNA adducts in esophageal squamous cell carcinoma (ESCC) in northeast Iran. Golestan Province in northeast of Iran has one of the highest esophageal cancer incidences in the world. The study included 93 ESCC cases and 50 control individuals who were seen at the clinical cancer center in Golestan province. NQO1 C609T genotypes were determi...

OBJECTIVE To assess the relationship between selenium (Se) concentration in rice and the incidence of esophageal cancer (EC) in a high risk area in Northern Iran. METHODS This ecological study was conducted in Golestan province of Iran in 2012. In this area, 45714 acres of land are cultivated by rice. A total of 69 rice samples were taken. We investigated Se concentrations by the voltammetric...

Background : Thyroid cancer is the most common type of endocrine cancer. We aimed to determine incidence rates thyroid across a 10-year period (2004-2013) in Golestan, Iran. Methods obtained data from Golestan Population-Based Cancer Registry (GPCR). Age-standardized (ASR) were calculated and reported per 100000 person-years. The Joinpoint software was used assess time trends, average annual pe...