Title: Are the effects of a non-drug multimodal activation therapy of dementia sustainable? Follow-up study 10 months after completion of a randomised controlled trial

Penile squamous cell carcinoma (pSCC) is a rare disease, making it difficult to establish a standard of care, particularly in the advanced stage. We report a case of pSCC with advanced lymph node metastasis treated with multimodal therapy consisting of combination chemotherapy, irradiation, and chemosurgery using Mohs' zinc chloride-containing paste. An 80-year-old male with a past history of l...

Fibromyalgia poses a challenge for therapy. Recent guidelines suggest that fibromyalgia should be treated within a multidisciplinary therapy approach. No data are available that evaluated multimodal treatment strategies of Integrative Medicine (IM). We conducted a controlled, nonrandomized pilot study that compared two inpatient treatment strategies, an IM approach that included fasting therapy...

CONTEXT Multimodal treatment for men with locally advanced prostate cancer (PCa) using neoadjuvant/adjuvant systemic therapy, surgery, and radiation therapy is being increasingly explored. There is also interest in the oncologic benefit of treating the primary tumor in the setting of metastatic PCa (mPCa). OBJECTIVE To perform a review of the literature regarding the treatment of the primary ...

Numerous algorithms have been proposed to solve the shortest-pathproblem; many of them consider a single-mode network and crispcosts. Other attempts have addressed the problem of fuzzy costs ina single-mode network, the so-called fuzzy shortest-path problem(FSPP). The main contribution of the present work is to solve theoptimum path problem in a multimodal transportation network, inwhich the co...

Morbidity and mortality rates associated with acute hip fracture remain high. Over the past decade, management of has shifted to emphasize prompt surgical treatment, multimodal analgesia reduce opioid use, incorporation enhanced recovery pathways. Preoperative evaluation focuses on acutely correctable problems, understanding that delaying surgery may worsen outcome. Prophylaxis venous thromboem...

Background and Objective: Perioperative chemotherapy has been increasingly practiced on gastric cancer (GC) in Western Countries where two third of the patients have locally advanced disease at diagnosis. The histological radiological evaluation tumor response to are both cornerstones this multimodal therapy predict oncological outcomes. This article aims review current regression grade (TRG) c...

Multimodal nanoprobes have attracted intensive attentions since they can integrate various imaging modalities to obtain complementary merits of single modality. Meanwhile, recent interest in laser-induced photoacoustic imaging is rapidly growing due to its unique advantages in visualizing tissue structure and function with high spatial resolution and satisfactory imaging depth. In this review, ...

OBJECTIVES Neuroblastoma (NBL) predominantly affects children under 5 years of age. Through multimodal therapy, including chemotherapy, radiotherapy, surgery, and peripheral blood stem cell transplantation, the survival rate in patients with NBL have improved while treatment-related complications have also increased. Treatment-related ototoxicity, mainly from cisplatin, can result in profound h...