OBJECTIVE To describe retinal changes in acute zonal occult outer retinopathy (AZOOR). METHODS We investigated retinal function and morphologic changes in 5 patients (mean age, 33.6 years) with AZOOR and acute visual field loss in 1 or more zones using Stratus optical coherence tomography, multifocal electroretinograms, full-field electroretinograms, and Goldmann perimetry. RESULTS Goldmann...

PURPOSE To investigate early changes of retinal function in myopic eyes, patients with various degrees of myopia underwent multifocal electroretinography (multifocal ERG). METHODS Thirty young patients (mean age, 26.1 years) were divided into three groups according to the degree of refractive error: emmetropia/low, medium, and high myopia. All groups were matched by sex and age. All subjects ...

PURPOSE To perform a detailed morphologic and functional evaluation of Best macular dystrophy (BMD) associated with mutations in the VMD2 gene. DESIGN Retrospective study. PARTICIPANTS The records of 16 patients with BMD and heterozygous VMD2 mutations (group 1) and 5 patients with Best-like lesions with no detectable disease-associated alterations in the VMD2 gene (group 2) were evaluated ...

PURPOSE To test the efficacy of the intravitreal dexamethasone (DEX) implant in patients with retinal vein occlusions (RVOs) who have failed multiple anti-vascular endothelial growth factor (anti-VEGF) treatments. METHODS A randomized exploratory study of ten patients with branch RVO or central RVO who received at least two previous anti-VEGF treatments and had persistent or unresponsive cyst...

PURPOSE To evaluate the functional changes in various morphologic types of idiopathic epiretinal membrane (ERM) by multifocal electroretinography (mfERG) and spectral-domain optical coherence tomography (SD-OCT). METHODS All patients (n = 71) with unilateral idiopathic ERM underwent complete ophthalmologic examination, including measurements of best-corrected visual acuity (BCVA), SD-OCT, and...

The authors evalute the visual functions of patients with unilateral central serous chorioretinopathy (CSC) and compare them with their non-affected eye and with a control group. Fourteen patients with CSC treated with direct laser-photocoagulation were examined preoperatively and followed-up, up to 2 years postoperatively. Baseline best corrected visual acuity (BCVA) and contrast sensitivity (...

data suggest that the multifocal electroretinography (mferg) may have a role in the assessment of patients with central retinal vein occlusion (crvo). to explore the mferg responses in patients with crvo. mferg responses were recorded at 61 discrete retinal locations from both eyes of 25 patients diagnosed with retinal vein occlusions within 3 weeks of onset. the latencies and amplitudes of ave...