background: health information system (his) has been utilized for collecting, processing, storing, and transferring the required information for planning and decision‑making at different levels of health sector to provide quality services. in this study, in order to provide high‑quality his, primary health care (phc) providers’ perspective on current challenges and barriers were investigated. m...

BACKGROUND The uptake of guideline recommendations that improve heart failure (HF) outcomes remains suboptimal. We reviewed implementation interventions that improve physician adherence to these recommendations, and identified contextual factors associated with implementation success. METHODS We searched databases from January 1990 to November 2017 for studies testing interventions to improve...

Aging is commonly defined as a time-dependent loss of physiological integrity, leading to the decline and impair in organism functions and to the increase of risk for cancer and other major age-associated diseases, finally increasing vulnerability to death [1]. During the last decade the intensive search of anti-aging remedies has lead to the conclusion that both the insulin/IGF-like signaling ...

Halofuginone is an analog of febrifugine-an alkaloid originally isolated from the plant Dichroa febrifuga. During recent years, halofuginone has attracted much attention because of its wide range of beneficial biological activities, which encompass malaria, cancer, and fibrosis-related and autoimmune diseases. At present two modes of halofuginone actions have been described: (1) Inhibition of S...

OBJECTIVE To systematically review the available evidence on paediatric early warning systems (PEWS) for use in acute paediatric healthcare settings for the detection of, and timely response to, clinical deterioration in children. METHOD The electronic databases PubMed, MEDLINE, CINAHL, EMBASE and Cochrane were searched systematically from inception up to August 2016. Eligible studies had to ...

BACKGROUND Prognostic models in reproductive medicine can help to identify subfertile couples who would benefit from fertility treatment. Expectant management in couples with a good chance of natural conception, i.e., tailored expectant management (TEM), prevents unnecessary treatment and is therefore recommended in international fertility guidelines. However, current implementation is not opti...

This paper has reviewed theoretical and empirical studies on information credibility with particular questions of how scholars have conceptualized credibility that is known as a multifaceted concept with underlying dimensions; how credibility has been operationalized and measured in empirical studies, especially in the Web context; what are the important user characteristics that contribute to ...

In this paper we discuss the multifaceted nature of vagueness, the limits of (standard) set theory in dealing with the foundational aspects that a really innovating theory of vagueness should manifest, and the difficulties in outlining the possible features that such a type of new formalism should exhibit in order to be able to deal with such innovative aspects. We shall highlight some aspects ...

Pain assessment is a multifaceted process. A common assumption is that all nurses have the same baseline knowledge about pain, a potentially erroneous assumption that influences clinical practice. Nurses have varied experiences in education and pain management. This article describes a research project conducted by the hospital's clinical nurse specialist group to evaluate the effects of a nurs...

Proposed object-oriented approaches are still in an initial stage of investigation and are mainly limited to modelling CAD applications which manipulate ill-deened, evolving and multifaceted objects. In this paper , we argue in favour of a model, called CEDAR, which aims at easing the modelling process by endowing object-oriented approach with a viewpoint notion. keywords: object-oriented datab...