The structural basis of DNA curvature remains elusive, because models for curvature based on crystallographic structures of molecules containing A tracts do not agree with any of the models for sequence-directed curvature based on solution studies. Here we demonstrate that the difference is probably due to MPD (2-methyl-2,4-pentanediol), the dehydrating agent commonly used in crystallography. O...

Methylphenidate (MPD) administration alters the subcellular distribution of vesicular monoamine transporter-2 (VMAT-2)-containing vesicles in rat striatum. This report reveals previously undescribed pharmacological features of MPD by elucidating its receptor-mediated effects on VMAT-2-containing vesicles that cofractionate with synaptosomal membranes after osmotic lysis (referred to herein as m...

This article presents the experimental observations and characterization of ion acoustic solitons (IASs) in a unique multi-pole line cusp plasma device (MPD), which magnitude pole-cusp magnetic field can be varied. In addition, by varying field, proportion two-electron-temperature components filament-produced plasmas MPD The are experimentally characterized measuring their amplitude-width relat...

The double-end partial discharge (PD) measurement method is the most common for measuring and localizing PD sources in power cables. sensitivity of sensor, processing speed data acquisition unit, localization algorithm are three main keys to ensuring accuracy source on A new multi-end known as segmented correlation trimmed mean (SCTM) has recently demonstrated excellent algorithm, however, only...

The Nuclotron-base Ion Collider fAcility (NICA) is under construction at the Joint Institute for Nuclear Research (JINR), with commissioning of facility expected in late 2022. Multi-Purpose Detector (MPD) has been designed to operate NICA and its components are currently production. detector be ready data taking first beams from NICA. This document provides an overview landscape investigation Q...

This study investigates the efficacy of optimal semi-active dampers for achieving the best results in seismic response mitigation of adjacent buildings connected to each other by magnetorheological (MR) dampers under earthquakes. One of the challenges in the application of this study is to develop an effective optimal control strategy that can fully utilize the capabilities of the MR dampers. H...

Mobile phone dependence (MPD) is a behavioral addiction that has become an increasing public mental health issue. While previous research has explored some of the factors that may predict MPD, the underlying neural mechanisms of MPD have not been investigated yet. The current study aimed to explore the microstructural variations associated with MPD as measured with functional Magnetic Resonance...

the rotational friction dampers can be improved the seismic behavior of the steel structures, and they can be reduced the internal forces in the bracing members, columns and the other structural members. in this research, a simple method for modeling and analysis of braced frames equipped by these dampers is proposed. the proposed model describes seismic behavior of dampers very well and it is ...

Methylphenidate (MPD) is the most prescribed drug for attention deficit hyperactivity disorder. Licit and illicit use also occurs during pregnancy, however the effects from this use on offspring development are unknown. To model late gestational exposure, Sprague-Dawley litters were treated with 0, 5, 10, 20, or 30mg/kg×4/day every 2h with MPD on postnatal days 11-20 (within-litter design; days...