Introduction: Nowadays radiosensitive polymer gels are used as a reliable dosimetry tool for verification of 3D dose distributions. Special characteristics of these dosimeters have made them useful for verification of complex dose distributions in clinical situations. The aim of this work was to evaluate the capability of a normoxic polymer gel to determine electron dose distributions in differ...

Translational Imaging Group, Centre for Medical Image Computing, University College London, London, UK In this work, we propose to tackle the problem of attenuation correction in the head and neck by synthesising CT from MR images using an iterative multi-atlas approach. The proposed method relies on pre-acquired T2-weighted MRI and CT images of the neck. For each subject, the MRI is non-rigidl...

Introduction: Despite the fact that the clinical implementation of polymer gel dosimetry has been facilitated after the introduction of normoxic gels, there are still complications in its clinical routine use that are under investigation. In the current work, the feasibility of using a normoxic polymer gel dosimeter named MAGICA has been investigated for use in our clinical brachytherapy applic...

PURPOSE To analyze intraoperative (IO) dosimetry using transrectal ultrasound (TRUS), performed before and after prostate low-dose-rate brachytherapy (LDR-BT), and compare it to dosimetry performed 30 days following the LDR-BT implant (Day 30). MATERIAL AND METHODS A total of 236 patients underwent prostate LDR-BT using 125I that was performed with a three-dimensional TRUS-guided interactive ...

Computed tomography (CT) dosimetry normally uses an ionization chamber 100 mm long to estimate the computed tomography dose index (CTDI), however some reports have already indicated that small devices could replace the long ion chamber to improve quality assurance procedures in CT dosimetry. This paper presents a novel dosimetry system based in a commercial phototransistor evaluated for CT dosi...

OBJECTIVE Estimation of activity accumulated in tumor and organs is very important in predicting the response of radiopharmaceuticals treatment. In this study, we synthesized (177)Lutetium ((177)Lu)-trastuzumab-iron oxide nanoparticles as a double radiopharmaceutical agent for treatment and better estimation of organ activity in a new way by magnetic resonance imaging (MRI). METHODS (177)Lu-t...

PURPOSE To check the bioeffects of the components of magnetic resonance imaging (MRI). MRI is based on an assumed harmless interaction between certain nuclei in the body when placed in a strong magnetic field and radio wave fields. There are three key factors actuating on the examining body: a powerful static magnetic field (SMF), magnetic gradient fields (MGFs), and pulsed radiofrequency (RF) ...

INTRODUCTION Magnetic resonance imaging (MRI) is increasingly used intraoperatively, because it provides excellent soft tissue distinction and on-the-fly adjustment to imaging slice orientation without exposing clinician or patient to radiation. For neurosurgical procedures, intraoperative MRI holds significant advantages over traditional stereotactic methods (e.g. compensation for brain shift)...