نتایج جستجو برای: mpla
تعداد نتایج: 134 فیلتر نتایج به سال:
Lyme disease, Borrelia burgdorferi-caused infection, if not recognized and appropriately treated by antibiotics, may lead to chronic complications, thus stressing the need for protective vaccine development. The immune protection is mediated by phagocytic cells and by Borrelia-specific complement-activating antibodies, associated with the Th1 immune response. Surface antigen OspC is involved in...
This paper discusses an approach to incremental learning in natural language processing. The techn ique of project ing and integrating semantic const ra in ts to learn word definitions is analyzed as Implemented in the POLITICS system. Extens ions and improvements of this technique are deve loped. The problem of generalizing ex i s t i ng word meanings and understanding metaphor ical uses of wo...
Synthetic forms of E. coli monophosphoryl lipid A (sMLA) weakly activate the MyD88 (myeloid differentiation primary response protein) branch of the bifurcated TLR4 (Toll-like receptor 4) signaling pathway, in contrast to diphosphoryl lipid A (sDLA), which is a strong activator of both branches of TLR4. sMLA's weak MyD88 signaling activity is apparent downstream of TLR4/MyD88 signaling as we sho...
For subunit vaccines, adjuvants play a key role in shaping immunological memory. Nanoparticle (NP) delivery systems for antigens and/or molecular danger signals are promising adjuvants capable of promoting both cellular and humoral immune responses, but in most cases the mechanisms of action of these materials are poorly understood. Here, we studied the immune response elicited by NPs composed ...
Abstract The development of a universal influenza vaccine to protect against variants will be the priority goal in combating virus infection. In this study, we exploited novel type protein nanoparticles consisting NP as core and NA1-M2e or NA2-M2e fusion proteins coating antigens by using an SDAD heterobifunctional crosslinker. Intramuscular immunization NP/NA-M2e (core/shell) induced increased...
El cine del escritor y antropólogo Ruy Duarte de Carvalho ha sido estudiado desde la perspectiva antropología contextualización histórica su función política en Angola los años setenta ochenta. En este trabajo quiero, complementariamente, examinar puesta forma. Las películas son obras urgencia, pero también un poeta para el que forma fílmica es importante: más allá facilitar circulación, contri...
We investigate the behavior of small perturbations around the Kaluza-Klein monopole in the five dimensional space-time. We find that the even parity gravitational wave does not propagate in the five dimensional space-time with Kaluza-Klein monopole provided that the gravitational wave is constant in the fifth direction. We conclude that a gravitational wave and a U(1) magnetic monopole do not c...
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