Mast cells (MCs) have been identified in various tumors; however, the role of these cells in tumorigenesis remains controversial. Here, we quantified MCs in human and murine malignant pleural effusions (MPEs) and evaluated the fate and function of these cells in MPE development. Evaluation of murine MPE-competent lung and colon adenocarcinomas revealed that these tumors actively attract and sub...

Mucuna pruriens Linn. (velvet bean) has been used by native Nigerians as a prophylactic for snakebite. Rats pretreated with M. pruriens seed extract (MPE) have been shown to protect against the lethal and cardiovascular depressant effects of Naja sputatrix (Javan spitting cobra) venoms, and the protective effect involved immunological neutralization of the venom toxins. To investigate further t...

Some clinical investigations have assessed the efficacy and safety of bevacizumab combined with platinum anti-cancer drugs versus platinum drugs alone in treating malignant pleural effusion (MPE) caused by lung cancer through intrapleural injection. This report is a meta-analysis of independent research conclusions. Eleven controlled trials with 769 MPE patients were included in this report. Po...

We study the Markov perfect equilibrium (MPE) of an alternating move, infinite horizon duopoly model where the strategic variable is quantity. We exhibit a pair of differencedifferential equations that, when they exist, differentiable MPE strategies satisfy. For quadratic payoff functions, we solve these equations in closed form and demonstrate that the MPE corresponding to the solution is the ...

Patients with a variety of malignancies can develop malignant pleural effusion (MPE). MPE cause significant symptoms and result in marked decrease quality life poor prognosis. is primarily considered as an immune vascular manifestation metastases. In the present review, existing evidence supporting applicability anti‑angiogenic therapy immunotherapy for treatment was summarized. have benefited ...

Parkinson’s disease (PD) results primarily from the death of dopaminergic neurons in substantia nigra. Treatment of PD has been shifted recently towards herbal medicines. Bacopa monnieri (L.) Wettst. (BM) and Mucuna pruriens (L.) DC (MP) are traditional herbal plants known to have neuroprotective effects due to the presence of bacosides in whole plant extract of Bacopa monnieri (BME) and L-DOPA...

Bu çalışmada püskürtmeli kurutucuda mikroenkapsüle edilmiş propolis ekstraktı (MPE) %0.05, %0.1 ve %0.2 oranlarında hazır muz aromalı puding formülasyonlarına katılmıştır. Bulgulara göre MPE düzeyinin artışına bağlı olarak depolama süresince örneklerinde nem içeriğinde azalma görülmüştür (p

Clinical history and physical examination are helpful in indicating the potential causes of pleural effusions (PEs). However, the accurate diagnosis and establishment of the causes of PE is an ongoing challenge in daily clinical practice. The primary aim of this study was to distinguish between infectious PE and malignant PE (MPE) by measuring two major acute phase response biomarkers: prealbum...

We recently discovered novel discriminative training criteria following a principled approach. In this approach training criteria are developed from error bounds on the global error for pattern classification tasks that depend on non-trivial loss functions. Automatic speech recognition (ASR) is a prominent example for such a task depending on the non-trivial Levenshtein loss. In this context, t...