UNLABELLED The importance of having tumor-free margins when resecting oral neoplasms has been known for decades. OBJECTIVE To correlate clinical and pathology data to surgical margin status in patients with squamous cell carcinoma of the tongue and floor of the mouth. METHOD This historical cohort cross-sectional study included all patients submitted to squamous cell carcinoma resection for...

Epidermoid cysts, true dermoid cysts and teratoid cysts compose the spectrum of cystic teratomas, which are defined as neoplasms whose tissue are derivatives of more than one germ layer, foreign to that part of the body from which the tumor arises. Epidermoid cysts of the floor of the mouth are rare lesions and are much less common than dermoid cysts in the head and neck. This case reports a 43...

Ameloblastomas are an enigmatic group of oral tumors. The name implies a resemblance to cells of the enamel-forming organ. The general agreement that ameloblastomas are odontogenic in origin occurs largely on the basis of the histologic similarities of the tumor and the developing enamel organ. Ameloblastomas show wide morphological spectra and may pose diagnostic difficulties. Of the many type...

Editor's Note: The editors invited two perspectives— one more detailed, one more open-ended—on the important article in this issue of the journal by Roblyer et al. on new imaging technology for neoplasia screening in the oral cavity. Whereas the perspective by the Rosin group (Poh et al.) puts autofluorescence imaging and the Roblyer et al. report under a figurative microscope, this different p...

This study was set up to investigate whether work as a stoker is associated with an increased risk of specific malignant neoplasms. For this purpose, a cohort of 2777 male stokers was followed up through a 10 year period with regard to cause specific mortality. Comparisons were made with another cohort of unskilled male workers in physically demanding jobs. The mortality of the stokers was sign...

Schwannomas, or neurilemmomas (as they are occasionally called), typically present as firm, encapsulated masses with a solid to partly cystic gross appearance. These benign neoplasms originate from Schwann cells, which develop during the fourth week of gestation during the ectomesenchymal detachment of the neural crest. They subsequently form an envelope around extracranial nerve fibers, provid...

a 22-year-old man presented with exertional dyspnea commencing one month prior to his admission. echocardiography revealed a non-homogenous mass, and the pathology examination of the pericardial biopsy was compatible with angiosarcoma.

Osteoid osteomas are benign skeletal neoplasms that are commonly encountered in the bones of the lower extremities, but are exceedingly rare in jaw bones with a prevalence of less than 1%. This unique clinical entity is usually seen in younger individuals, with nocturnal pain and swelling as its characteristic clinical manifestations. The size of the lesion is rarely found to be more than 2 cm....

BACKGROUND Beckwith-Wiedemann syndrome (BWS) is a rare disorder characterized by macrosomia, macroglossia, visceromegaly, and omphalocele and an increased risk of growing tumors. Prenatal and postnatal high levels of serum alpha-fetoprotein are associated with several diseases and neoplasms including hepatoblastomas and other hepatic tumors. The diagnosis of BWS is usually made in the postnatal...