The cortical motor system of primates is formed by a mosaic of anatomically and functionally distinct areas. These areas are not only involved in motor functions, but also play a role in functions formerly attributed to higher order associative cortical areas. In the present review, we discuss three types of higher functions carried out by the motor cortical areas: sensory-motor transformations...

Twenty patients with myotonic muscular dystrophy (MMD) were compared with twenty controls on a battery of standardised neuropsychiological tests measuring motor and cognitive functions. The MMD patients performed significantly poorer on both motor and cognitive tests, particularly those assessing spatial functions. Although both motor and cognitive scores were correlated with age, significant d...

objective: the cerebellum is a key structure involved in coordinated motor planning, cognition, learning and memory functions. this study presents a permanent model of a toxin produced cerebellar lesion characterized according to contemporary motor and cognitive abnormalities. materials and methods: in this experimental study, slow administration of quinolinic acid (qa, 5 μl of 200 μmol, 1 μl/m...

a spinal cord injury (sci) refers to any injury to the spinal cord or nerves at the end of the spinal canal that is caused by trauma instead of disease often causes permanent changes in strength, sensation and other body functions below the site of the injury. road traffic collision (rtc) or car crash occurs when a vehicle collides with another vehicle, pedestrian, animal, road debris, or other...

Handwriting is an integral part of every child's school experience. In order to provide the best program to children both with and without handwriting problems, elementary educators need to understand the factors underlying the skill of handwriting. This study investigated the relationship between the cognitive understanding of locatives (e.g., words used for spatial and temporal concepts, such...

[Purpose] This study attempted to investigate the effect of physical therapy frequency based on neurodevelopmental therapy on gross motor function in children with cerebral palsy. [Subjects and Methods] The study sample included 161 children with cerebral palsy who attended a convalescent or rehabilitation center for disabled individuals or a special school for children with physical disabiliti...

Multiple factors simultaneously affect the spiking activity of individual neurons. Determining the effects and relative importance of these factors is a challenging problem in neurophysiology. We propose a statistical framework based on the point process likelihood function to relate a neuron's spiking probability to three typical covariates: the neuron's own spiking history, concurrent ensembl...

[Purpose] This study examines the effect of concentric and eccentric control training of the paretic leg on balance and gross motor function in children with spastic hemiplegia. [Subjects and Methods] Thirty children with spastic hemiplegia were randomly divided into experimental and control groups. In the experimental group, 20 min of neurodevelopmental therapy and 20 min of concentric and ecc...

BACKGROUND In children with cerebral palsy (CP), stiffness, caused by contractile and non-contractile structures, can influence motor performance. This study sought to determine whether the nerve mobility had a relevant impact on motor performance in children with CP. We hypothesized that a positive Straight Leg Raise (SLR) test, as well as smaller SLR hip angle, would relate to lower leg muscl...

The use of quantitative neuroimaging (volumetry), motor, and oculomotor assessments for studying children with attention-deficit/hyperactivity disorder (ADHD) has grown dramatically in the past 20 years. Most evidence to date suggests that anomalous basal ganglia development plays an important role in early manifestation of ADHD; however, widespread cerebellar and cortical delays are also obser...