Objective. To evaluate the safety and efficacy of abatacept plus methotrexate (MTX) over 5 years in patients with rheumatoid arthritis. Methods. Patients were randomized to abatacept 10 or 2 mg/kg or placebo, plus MTX. Patients completing the 1-year, double-blind period entered the longterm extension, where all patients received a fixed dose of abatacept ~10 mg/kg. We describe safety analyses f...

Scientific creation battles the worldview of naturalism at the level of scientific fact and theory, but crucial battlegrounds are also found in the foundational concepts that shape the method and direction of science. One of these is summarized by the term “naturalism.” This debate is hindered by equivocal terminology, presuppositional inconsistency, and the use of secular premises by some Chri...

Residues of glyphosate, a potent herbicide, are increasingly found in diverse environments.Glyphosate residues soil alter plant physiological processes; however, their effects on defense strategies and subsequent species interactions poorly understood.Glyphosate inhibition the shikimate pathway affects defense-related phytohormones phenylpropanoid pathway, basis for many phytoalexins.Glyphosate...

Previous work on group technology choice, such as task-technology fit (Goodhue 1995; Zigurs and Buckland 1998), has typically taken a deterministic perspective, failing to substantively consider the impact of individual differences among team members in terms of experience, knowledge, and/or perceptions of the group’s task and technology choices. We attempt to fill this gap in the literature by...

The purpose of this study was to look for personality variables that characterized young adults with learning disabilities and test anxiety. Fifty-four Israeli adults diagnosed with learning disabilities participated in the study, 24 of them were diagnosed as having test anxiety; 30 did not have test anxiety. The participants completed the Test Anxiety Inventory (TAI) to validate the diagnosis ...

Three studies examined the relationship between individuals’ perceived “prototypicality” in a group, their subsequent self-presentation goals, and individual effort in that group. Consistent with the finding that feelings of marginal ingroup membership status elicit a desire to seek stronger social connections within ingroups, we predicted that non-prototypical group members will have more sali...

Anthropomorphic beliefs about objects lead people to treat them as if they were alive. Two experiments test how anthropomorphic thought affects consumers’ product replacement intentions. Consumers induced to think about their car in anthropomorphic terms (i) were less willing to replace it and (ii) gave less weight to its quality when making replacement decisions. Instead, they (iii) attended t...

Little empirical research has examined the implicit effects of environmental cues on consumer behavior. Across six studies using a combination of field and laboratory methods, the authors find that products are more accessible, evaluated more favorably, and chosen more frequently when the surrounding environment contains more perceptuallyor conceptuallyrelated cues. The findings highlight the i...

In the present experimental study, it was investigated whether virtual groups, depending on their situational circumstances, were able to decide in favor of the more suitable problem-solving procedure for their situation. The situational circumstances were to either have the possibility to create a “knowledge and information awareness” approach or not, that is, an approach that provides to the ...

Attempts to evaluate the cognitive-motivational profiles of students with reading comprehension difficulties have been scarce. The purpose of the present study was twofold: (a) to assess the discriminatory validity of cognitive, motivational, affective, and psychopathological variables for identification of students with reading difficulties, and (b) to profile students with and without reading...