introduction and aims: gastroesophageal reflux disease (gerd) is very common in western countries. gerd is increasing, has profound effects on health economics, disturbs the patient's health-related quality of life, and increases the risk for development of esophageal adenocarcinoma. gerd is considered to be infrequent in developing countries. this study was performed to determine the prevalenc...

background: gastroesophageal reflux disease (gerd) is one of the most prevalent disorders affecting gastrointestinal tract with a wide range of frequency around the world. in this study, we aimed to review all of the published studies about gerd’s prevalence in iran systematically. methods: we searched bibliographic databases including pubmed and google scholar and local databases (scientific i...

Gastroesophageal reflux is the involuntary movement of gastric contents to the esophagus. It is a common disease, occurring in one third of the population in the United States. However, reflux is only considered a disease when it causes frequent or severe symptoms or when it produces injury. About 3–7% of the U.S. population suffers from frank esophageal reflux disease. Most reflux disease is n...

Gastroesophageal reflux disease often presents as heartburn and acid reflux, the so-called "typical" symptoms. However, a subgroup of patients presents a collection of signs and symptoms that are not directly related to esophageal damage. These are known collectively as the extraesophageal manifestations of gastroesophageal reflux disease. Principal among such manifestations are bronchospasm, c...

Introduction: Gastroesophageal reflux (GER) is the most common esophageal disorder, which occurs at all ages. GER is defined as the passage of gastric contents into the esophagus. GER disease (GERD), which is a long-term complication, is a common pediatric problem. Clinical manifestations of GERD in infants include regurgitation, irritability, choking, gagging, vomiting, poor weight gain, and r...

Patients with gastroesophageal reflux disease may have disturbances of gastric motility, which could play a role in the pathophysiology of the disease. Recent studies have suggested that the gastric region just below the gastroesophageal junction may have a distinct physiological behavior. We determined whether patients with gastroesophageal reflux disease have abnormal residence of food in the...

HYPOTHESIS There is an independent association between the different patterns of esophageal acid exposure in gastroesophageal reflux disease and the severity of the disease. DESIGN Case-comparison study. SETTING Department of surgery at a university hospital. PATIENTS A group of 401 patients with increased esophageal acid exposure divided into 4 groups according to the pattern of reflux: ...

BACKGROUND Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal pathology in infants and young children. Ultrasonography (US) has been considered to be a reliable diagnostic tool for GERD but the severity of GERD and the clinical implications based on imaging findings has not been evaluated. AIMS To compare the diagnostic value of lower esophageal US with that of ...