the present work describes the studies on the coordination behaviour of 4[n-(benzalidene) amino]antipyrine semicarbazone (baaps) (i), 4[n-(furfural)amino]antipyrine semicarbazone (ffaaps) (ii) and 4[n-(cinnamalidene)amino]antipyrine semicarbazone (caaps) (iii) in presence of dimethyl sulfoxide (dmso) or diphenyl sulfoxide (dpso) towards th4+ and uo22+ salts. all the complexes were isolated in n...

aromatase inhibitors (ais) as effective candidates have been used in the treatment of hormone-dependent breast cancer. in this study, we have proposed 300 structures as potential ais and filtered them by lipinski’s rule of five using druglito software. subsequently, they were subjected to docking simulation studies to select the top 20 compounds based on their gibbs free energy changes and also...

Herein, the pyridinophane tetradentate ligand PyNMe 3 is used to isolate and structurally characterize well-defined organometallic Ni( ii ) iii complexes bearing cycloneophyl fragment, an alkyl/aryl C-donor ligand.

a new schiff base ligand, 2,2'-{pyridine-2,6-diylbis[nitrilo(e)methylylidene]}bis(4 bromophenol),has been synthesized by reaction of the 2,6-diamino pyridine with 5-bromo salicylaldehyde at ethanolunder refluxing. the structure of the synthesized compound resulted from the ir, 1hnmr, ms anduv spectroscopy and elemental analysis data. formation constant (kf) value of it’s complexes withcu2+, ni2...

the complexation reactions between diacetyl monooxime (damo), imidazole (him), histamine (hist) and histidine (his) with co2+, ni2+ and cu2+ were studied potentiometrically in aqueous solution at 25 °c and m= 0.5 m kno3. the overall stability constants log b's of species were obtained by computer refinement of ph-volume data using best computer program. several models were tested and, based on ...

in present studies the synthesis, characterization and biological properties ofoxovanadium(iv) coordination compounds of 4[n-(4′-ethylbenzalidene)amino] antipyrinethiosemicarbazone (ebaapts) and 4[n-(2′,4′-dimethylbenzalidene)amino] antipyrinethiosemicarbazone (dmbaapts) with the general composition vox2l (x = c1-, br-, i-, no3-or ncs-) and vo(cio4)2(l)h2o (l = ebaapts or dmbaapts) are describe...

objectives thus, the present study aimed to determine if fas and fasl promoter polymorphisms are associated with the clinical outcome of hbv infection. patients and methods dna samples were obtained from the infected individuals including chronic carrier (n = 50), chronic hepatitis (n = 50), cirrhosis (n = 25), naturally recovered (n = 26) and compared with those of their matched healthy contro...

in this study at first , an azo dye, 2,7- naphthalenediol, 2-[(4-bromophenyl)azo (bpand) as a ligand has been synthesized by addition of p-bromoaniline to the modified montomorillonite k10 clay. this ligand was characterized using 1h-nmr, uv-vis and ir spectroscopies. subsequently, its interaction with calf thymus deoxyribonucleicacid ,ct-dna was investigated in 5 mm phosphate buffer solution, ...