PURPOSE We analyzed the impact of immediate intravesical mitomycin C instillation after transurethral resection of the bladder (TURB) on tumor recurrence and progression in patients with periodic mitomycin C instillation. MATERIALS AND METHODS Between June 2000 and June 2006, a retrospective study was performed in a total of 115 patients with primary bladder tumors receiving a 6-week course o...

conclusions the intervention bundle prompted increased administration of psdivc and documentation. similar centres may benefit from an intervention to improve compliance. results sixty-four patients in group a underwent turbt prior to introduction of the intervention bundle. fifty-four patients had non-muscle invasive bladder cancer (nmibc), which would have been eligible for psdivc. fifteen (2...

introduction: otorrhea and granulation tissue in canal wall down mastoidectomy (cwd) is the common problem in cholesteatoma removal and leads to many discomfort for both the patient and the physician. the main objective in cwd is creating the dry cavity, so the topical antibiotic and acetic acid in variable saturations are used for this purpose. in this study we evaluate the effectiveness of to...

Non-small-cell lung cancer (NSCLC) is the leading cause of death from cancer in the United States. Chemotherapy prolongs survival among patients with advanced disease, but at the cost of clinically significant adverse effects. As a novel promising oncotherapy method, induced differentiation by mitomycin C has been applied for NSCLC therapy at recent year. In this study, the molecular mechanism ...

BACKGROUND Airway granulation tissue and scar formation pose a challenge because of the high incidence of recurrence after treatment. As an emerging treatment modality, topical application of mitomycin C has potential value in delaying the recurrence of airway obstruction. Several animal and clinical studies have already proven its feasibility and efficacy. However, the ideal dosage has still n...

AIMS To compare the rate of recurrence and complication after surgery for primary pterygium performed by one surgeon using either intraoperative mitomycin C or beta irradiation. METHODS A retrospective study was performed of 164 eyes in 164 patients who had undergone primary pterygium surgery. After the pterygium was excised, the bare sclera was covered by sliding adjacent superior conjunctiv...

BACKGROUND The purpose of this study was to investigate the role of intraoperative application of mitomycin C in prevention of glottic restenosis after posterior transverse CO2 laser cordotomy (PTLC) for patients with post-thyroidectomy bilateral vocal fold paralysis. METHODS Twenty-five patients with an impaired airway because of bilateral vocal fold paralysis were treated with PTLC. Patient...