BACKGROUND Historical biogeography and evolutionary processes of cave taxa have been widely studied in temperate regions. However, Southeast Asian cave ecosystems remain largely unexplored despite their high scientific interest. Here we studied the phylogeography of Leopoldamys neilli, a cave-dwelling murine rodent living in limestone karsts of Thailand, and compared the molecular signature of ...

A new quadrannulate species of Orobdella, Orobdellamasaakikuroiwai sp. n., from the mountainous region of central Honshu, Japan is described. This is only the second small species known within this genus, with a body length of less than 4 cm for mature individuals. Phylogenetic analyses using nuclear 18S rDNA and histone H3 as well as mitochondrial COI, tRNA(Cys), tRNA(Met), 12S, tRNA(Val), 16S...

A large-type sexannulate leech species, Orobdella ibukifukuyamai sp. nov. , from Kii-Oshima Island, Japan, is described based on morphologic and molecular data. Phylogenetic analyses using nuclear 18S rRNA, 28S histone H3, mitochondrial cytochrome c oxidase subunit I, tRNA Cys Met 12S Val 16S Leu NADH dehydrogenase 1 markers showed that O. formed a clade with the okanoi Nakano, 2016 yamaneae oc...

INTRODUCTION been carried out with anthocyanin as a marker of vacuolar material and with various enzymes as markers of mitochondrial and hyaloplasmic commethod of isolating cell organelles (2) and its markers of mitochondrial and hyaloplasmic commodification for use in isolating chloroplasts (3, ponents 5, 13), it has been used extensively in the study visual observations of the purity of these...

Endometrial carcinoma (EC) is a solid neoplasia for which a role for mitochondria in cancer progression is currently emerging and yet represents a diagnostic and prognostic challenge. EC is one of the most frequently occurring gynecological malignancies in the Western world whose incidence has increased significantly during the last decades. Here, we review the literature data on mitochondrial ...

BACKGROUND Macrophage polarization plays a pivotal role in the process of inflammation which is common in chronic kidney disease (CKD). Macrophages polarization under the condition of CKD remains poorly understood. Here we tested the hypothesis that CKD promotes macrophage M1 polarization. METHODS A rat model of CKD was established by reduced renal mass (RRM). Polarization of macrophages was ...

Terranigra kosovica Radoman, 1978, was known from four localities in Kosovo. The monotypic genus described on the basis of genital morphology. We collected T. at a new locality, about 40 km its type locality. shell morphology, as well soft part morphology and anatomy were identical to that by Radoman. molecular markers mitochondrial cytochrome oxidase subunit I (COI) nuclear histone (H3) resolv...

All-trans-retinoic acid (atRA) is the active metabolite of vitamin A. The liver is the main storage organ of vitamin A, but activation of the retinoic acid receptors (RARs) in mouse liver and in human liver cell lines has also been shown. AlthoughatRA treatment improves mitochondrial function in skeletal muscle in rodents, its role in modulating mitochondrial function in the liver is controvers...

Acute kidney injury (AKI) contributes to the high morbidity and mortality of multi-system organ failure in sepsis. However, recovery of renal function after sepsis-induced AKI suggests active repair of energy-producing pathways. Here, we tested the hypothesis in mice that Staphyloccocus aureus sepsis damages mitochondrial DNA (mtDNA) in the kidney and activates mtDNA repair and mitochondrial bi...

Abstract The sterile insect technique (SIT) is widely used in integrated pest management programs for the control of Mediterranean fruit fly (medfly), Ceratitis capitata . genetic interactions between released individuals from sexing strains (GSS), SIT applications worldwide, and wild have not been studied. Under hypothesis that a number Vienna GSS to field might be completely may produce viabl...