objective(s): the aim of the present study was to prepare, characterize, and evaluate solid lipid nanoparticles (slns) containing zataria multiflora essential oil (zeo). materials and methods: in this study, z. multiflora essential oil-loaded solid lipid nanoparticles (ze-slns) were prepared to improve its efficiency in controlling some fungal pathogens. slns containing z. multiflora essential ...

conclusions although previous studies have shown that a-g transition mutations in 23 srrna gene (domain v) are the main reason for the occurrence of high level macrolides resistance in b. pertussis, however, the mentioned single nucleotide polymorphisms (snps) have not been detected in our resistant strain. this is the first report of high level macrolide resistant b. pertussis, without snps in...

in this study, we investigated the antifungal effects of silver nanoparticles (ag-nps) on candida albicans (atcc 5027), saccharomyces cerevisiae (atcc 5027). investigating method by using minimum inhibitory concentration (mic) technique, some of drugs including amphotericin b, fluconazole and synthesized ag-nps have been obtained on the fungi and the changes on membrane reactions of yeasts have...

A survey of 303 urban and 156 rural children showed nasopharyngeal carriage of relatively resistant Streptococcus pneumoniae organisms in 14.2% and 19.2% of children, respectively. These organisms have minimum inhibitory concentrations for penicillin in the range of 0.12-1 microgram/ml. An analysis of 40 relatively resistant S. pneumoniae strains showed resistance to co-trimoxazole in 47.5%, tr...

This work described a simple and efficient method for the synthesis of 1-azabicyclo[3.1.0]hexane-3-ene derivatives. arylidenmalononitriles and hydroxylamine hydrochloride in the presence of NaOH, under microwave irradiation and solvent-free conditions produced the titled compounds in good to excellent yields. Using of simple chemicals, short reaction times, and solvent-free conditions, high yie...

BACKGROUND Fluoroquinolones are a guideline-recommended therapy for complicated urinary tract infections, including pyelonephritis. Elevated drug concentrations of fluoroquinolones in the urine and therapy with high-dose levofloxacin are believed to overcome resistance and effectively treat infections caused by resistant bacteria. The ASPECT-cUTI phase 3 clinical trial (ClinicalTrials.gov, NCT0...

dermatophyte fungi are the etiologic agents of skin infections commonly referred to as ringworm. these infections are not dangerous but as a chronic cutaneous infections they may be difficult to treat and can also cause physical discomfort for patients. they are considered important as a public health problem as well. no information is available regarding the efficacy of antifungal agents again...

this study was carried out to evaluate the antimicrobial and antioxidant effectiveness of methanolic extract and different fractions (n-butanol, ethyl acetate, chloroform and n-hexane) of c.intybus seeds. the antimicrobial activity was determined by the disc diffusion method and minimum inhibitory concentration (mic) against a panel of microorganisms (four bacterial strains, i.e. p. multocida, ...

objective: teucrium polium l. (family lamiaceae) is a wild-growing flowering plant, found abundantly in south-western asia, europe and north africa. traditionally, t. polium has been used for different pathological conditions such as gastrointestinal disorders, inflammations, diabetes and rheumatism. the purpose of this study was to evaluate the antimicrobial effect of ethanol extract of teucri...