background: this study was conducted to determine the efficacy of milk thistle seeds (mtss) in counteracting the toxic effects of aflatoxin b1 (afb1) in a contaminated diet fed to broilers.methods: two dietary inclusion rates of afb1 (0, 0.250 and 500 ppb) and mts (0, 0.5 and 1%) were tested in a 3×3 factorial manner. the effect of nine experimental treatments was assessed using 216 one-d-old r...

Previously we have shown that perorally administered silymarin, a mixture of flavonolignans extracted from the seeds of Silybum marianum, possesses a hypocholesterolemic effect in rats fed high cholesterol diet enriched with fat. The aim of this paper was to complete the data concerning peroral and parenteral administration of silymarin. The rats fed standard laboratory diet did not respond to ...

The standardized extract contains flavonolignans, collectively referred to as silymarin. Sometimes the extract itself is called “silymarin”, which can lead to confusion over dosage since the level of flavonolignans (silymarin) in the extract is typically 60 to 80%, depending on the test methodology used. The main flavonolignans found in the extract are silybin (silibin), silychristin, silydiani...

The flavolignans silybin (1) and 2,3-dehydrosilybin (2) (Figure 1) were isolated from fruits of milk thistle [Silybum marianum (L). Gaertn.] cultivated in the Samara region (Russian Federation). 2,3-dehydrosilybin (2) for the first time in Russian Federation is described for the given plant. Silybin and 2,3-dehydrosilybin and also new preparation, a fluid extract of Silybum marianum fruits, hav...

Silymarin ‘milk thistle’ (Silybum marianum) plant, has been used for years treatment of different diseases such as liver and gallbladder disorders, protecting against snake bite insect stings, mushroom poisoning alcohol abuse. antioxidant, anti-lipid peroxidative, antifibrotic, anti-inflammatory, immunomodulatory, regeneration activities. The cardioprotective activities silymarin were primarily...

in order to study individual and integrated effects of biological, organic and chemical fertilizers on milk thistle (silybum marianum l.) quantitative and qualitative traits, a field experiment was conducted at research station, faculty of agriculture, ferdowsi university of mashhad, iran during growing season of 2010-2011. a complete randomized block design with twelve treatments and three rep...

Understanding spatial and temporal variation in factors influencing plant regeneration is critical to predicting plant population growth. We experimentally evaluated seed limitation, insect herbivory, and their interaction in the regeneration and density of tall thistle (Cirsium altissimum) across a topographic ecosystem productivity gradient in tallgrass prairie over two years. On ridges and i...

Plants are a valuable source of pharmaceuticals, food ingredients, agrochemicals, insecticides, flavors and pigments. These compounds are called secondary metabolites. These are compounds with a restricted occurrence in taxonomic groups that are not essential for an organism to live but play a role in the interaction of the organism with its environment, ensuring the survival of the organism in...