Chronic suppurative otitis media (CSOM) is a clinical condition where a patient suffers from external and middle ear infection caused mostly by bacteria or by fungi resulting in ear discharge. Identification of the causative microorganism and initiation of appropriate antimicrobial chemotherapy is needed in patients suffering from CSOM. Infections of the ear if happen to be chronic in nature ha...

An exciting biological advancement in the last few years is the use of microarray technologies to measure simultaneously the expression levels of thousands of genes The bottleneck now is how to extract useful information from the resulting large amounts of data An important and common task in analyzing microarray data is to identify genes with altered expression under two experimental condition...

Acute otitis media is usually considered a simple bacterial infection that is treated with antibiotics. However, ample evidence derived from studies ranging from animal experiments to extensive clinical trials supports a crucial role for respiratory viruses in the etiology and pathogenesis of acute otitis media. Viral infection of the upper respiratory mucosa initiates the whole cascade of even...

objective: generated acoustic trauma by suction and drill may cause sensorineural hearing loss after tympanomastoid surgery. this study was carried out to determine the relationship of sensorineural hearing loss and chronic otitis media surgery at ahvaz jundishapur university of medical sciences in iran. material and methods: this prospective study included 386 patients of chronic middle ear di...

Abstract Mucormycosis is an opportunistic fungal infection that often affects the nose and paranasal sinuses. The disease prevalence was very high in India during coronavirus 2019 pandemic, thereby raising public awareness about this disease. general practitioners were updated characteristics requirement for emergency management. Yet, some instances, treatment inadequate due to delayed presenta...

Eustachian tube dysfunction can cause fluid to collect within the middle ear cavity and form a middle ear effusion (MEE). MEEs can persist for weeks or months and cause hearing loss as well as speech and learning delays in young children. The ability of a physician to accurately identify and characterize the middle ear for signs of fluid and/or infection is crucial to provide the most appropria...

Hyperplasia of the middle ear mucosa contributes to the sequelae of acute otitis media. Understanding the signal transduction pathways that mediate hyperplasia could lead to the development of new therapeutic interventions for this disease and its sequelae. Endotoxin derived from bacteria involved in middle ear infection can contribute to the hyperplastic response. The p38 mitogen-activated pro...