نتایج جستجو برای: microvessel density

تعداد نتایج: 411523  

Journal: :Blood 2000
T Padró S Ruiz R Bieker H Bürger M Steins J Kienast T Büchner W E Berdel R M Mesters

The importance of angiogenesis for the progressive growth and viability of solid tumors is well established. In contrast, only few data are available for hematologic neoplasms. To investigate the role of angiogenesis in acute myeloid leukemia (AML), bone marrow biopsies from 62 adults with newly diagnosed, untreated AML (day 0) were evaluated. Further studies were done after the completion of r...

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2017
Huayue Lin Zanxi Fang Yuanhui Su Peihua Li Jingkun Wang Hongfeng Liao Qing Hu Chunlei Ye Yizhen Fang Qing Luo Zhiyuan Lin Chao Pan Fen Wang Zhong-Ying Zhang

We previously reported that overexpression of DHX32 contributes to the growth and metastasis of colorectal cancer (CRC). However, the underlying mechanism is not largely characterized. Herein, we reported that DHX32 in CRC cells upregulated expression of vascular endothelial growth factor A (VEGFA) at the transcription level through interacting with and stabilizing β-catenin. This promoted the ...

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Journal: :Folia histochemica et cytobiologica 2004
Marta Rzeszutko Wojciech Rzeszutko Piotr Dziegiel

Angiogenesis represents an important process manifested in tumour growth and in development of metastases. Using immunohistochemistry, the authors evaluated number of vessels in various nodular lesions of the thyroid (54 cases). Expression of CD34 antigen and microvessel density were evaluated in sections of archival paraffin blocks originating from the Department of Pathological Anatomy, Unive...

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Journal: :International Journal of Cancer 2000

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Journal: :Clinics 2016

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Journal: :Journal of clinical pathology 2005
E Cristi G Perrone G Toscano A Verzì S Nori D Santini G Tonini A Vetrani A Fabiano C Rabitti

AIMS Tumour angiogenesis is essential for carcinogenesis and facilitates the process of tumour development and metastasis. Vascular endothelial growth factor (VEGF) is a well characterised angiogenetic factor and is known to play a crucial role in new vessel development. To gain further insight into the effects of microvessel density and VEGF expression in colon cancer, their relation with tumo...

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Journal: :SAGE Open Medicine 2014

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Journal: :medical journal of islamic republic of iran 0
f sari aslani from the department of pathology, shiraz university of medical sciences, shiraz, i.r. iran. a aledavood

basal cell carcinoma (bcc) is currently the most common cutaneous cancer found in humans. although it generally shows a relatively benign course (bccl), some cases show aggressive behavior (bcc2). until recently, traditional histologic diagnostic criteria have failed to discriminate unequivocally between bcc 1 and bcc2. in this study we selected 50 cases of bcc and categorized them into two gro...

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Journal: :Cancer research 2000
M I Koukourakis A Giatromanolaki P E Thorpe R A Brekken E Sivridis S Kakolyris V Georgoulias K C Gatter A L Harris

Vascular endothelial growth factor (VEGF) is an important angiogenic factor, linked to poor outcome in human malignancies including non-small cell lung carcinoma (NSCLC). We used the 11B5 monoclonal antibody recognizing the VEGF/KDR complex (R. A. Brekken et al., Cancer Res., 58: 1952-1959, 1998) to assess the VEGF expression in cancer cells and the VEGF/KDR activated microvessel density (aMVD)...

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2013
Daniella FL Barbosa Lidia H Pulz Nilton P Santos Silvia Regina Kleeb José Guilherme Xavier José Luiz Catão-Dias Ricardo F Strefezzi

Background Mast cell tumors represent almost 25% of canine skin neoplasms. These tumors are classified in three grades of differentiation, based on histological features. However, this grading system is a method based on subjective parameters, which generate intraand interobserver variations. The microcirculation is an important feature to the primary tumor expansion, dissemination and metastas...

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  • " +i+ "
    • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->