MicroRNAs (miRNAs) represent a new class of noncoding RNAs encoded in the genomes of plants, invertebrates, and vertebrates. MicroRNAs regulate translation and stability of target mRNAs based on (partial) sequence complementarity. Although the number of newly identified miRNAs is still increasing, target mRNAs of animal miRNAs remain to be identified. Here we describe 31 novel miRNAs that were ...

micrornas (mirnas) are a group of short non-coding rnas implicated in numerous fundamental cellular processes, and their disregulations have been linked to several pathologic conditions, mainly cancers. determining tissue distribution of mirnas is a prerequisite for understanding their exact functions during development, tissue homeostasis and abnormality. in situ hybridization is a powerful te...

Banerjee J, Chan YC, Sen CK. MicroRNAs in skin and wound healing. Physiol Genomics 43: 543–556, 2011. First published October 19, 2010; doi:10.1152/physiolgenomics.00157.2010.—MicroRNAs (miRNAs) are small endogenous RNA molecules 22 nt in length. miRNAs are capable of posttranscriptional gene regulation by binding to their target messenger RNAs (mRNAs), leading to mRNA degradation or suppressio...

MicroRNAs (miRNAs) are an evolutionarily conserved class of small, regulatory non-coding RNAs that negatively regulate protein coding gene and other non-coding transcripts expression. miRNAs have been established as master regulators of cellular processes, and they play a vital role in tumor initiation, progression and metastasis. Further, widespread deregulation of microRNAs have been reported...

MicroRNAs (miRNAs) are known as single-stranded RNA molecule functional in all steps of plant life including growth, development, and stress responses. Plant genomes harbor hundreds miRNAs, which have diverse functions regulating numerous biological processes. After being first discovered plants by the year 2002, thousands miRNAs been identified so far. With help recent advances high-throughput...

MicroRNAs (miRNAs) are small single-stranded, non-coding RNA molecules involved in the pathogenesis and progression of cancer, including osteosarcoma. We aimed to clarify pathways involving miRNAs using new bioinformatics tools. applied WikiPathways PathVisio, two open-source platforms, analyze osteosarcoma miRTar ONCO.IO as integration found 1298 records papers associated with word “miRNA”. In...

  Objective(s): Erythropoiesis is regulated by some extrinsic and intrinsic factors as microRNAs (miRNAs). miRNAs are endogenously small non-coding regulatory RNAs which play vital roles in the variety of cellular fate, critical processes; growth, apoptosis, metabolism, survival of the cells and specially differentiation. Several miRNAs such as miR-16 and miR-451 have been shown to be correlate...

MicroRNAs (miRNAs) are an abundant class of approximately 22-nucleotide regulatory RNAs found in plants and animals. Some miRNAs of plants, Caenorhabditis elegans, and Drosophila play important gene-regulatory roles during development by pairing to target mRNAs to specify posttranscriptional repression of these messages. We identify three miRNAs that are specifically expressed in hematopoietic ...

In a recent study, plant microRNAs (miRNAs) have been found in the sera and tissues of various animals including humans. These miRNAs are acquired orally by food intake and can pass through the mammalian gastrointestinal tract into sera and organs. In vitro and in vivo studies have demonstrated that these plant microRNAs in food can regulate the expression of target genes in mammals. Correct re...