Early osteoporosis diagnosis is of important significance for reducing fracture risk. Image analysis provides a new perspective for noninvasive diagnosis in recent years. In this article, we propose a novel method based on machine-learning method performed on micro-CT images to diagnose osteoporosis. The aim of this work is to find a way to more effectively and accurately diagnose osteoporosis ...

With the development of hybrid imaging scanners, micro-CT is widely used in locating abnormalities, studying drug metabolism, and providing structural priors to aid image reconstruction in functional imaging. Due to the low contrast of soft tissues, segmentation of soft tissue organs from mouse micro-CT images is a challenging problem. In this paper, we propose a mouse segmentation scheme based...

Recently, very thin single crystal scintillator imaging plates became of great interest. Such thin screens are mainly used in micro-CT and nano-CT systems with either micro-focus X-ray tubes or with synchrotron sources. This work deals with a high resolution CCD camera in conjunction with a macro optical system and YAG:Ce single crystal scintillators for low energy X-ray micro-radiography appli...

Microcomputed tomography (Micro-CT) has the potential to noninvasively image the structure of organs in rodent models with high spatial resolution and relatively short image acquisition times. However, motion artifacts associated with the normal respiratory motion of the animal may arise when imaging the abdomen or thorax. To reduce these artifacts and the accompanying loss of spatial resolutio...

Micro-CT is widely used in preclinical studies, generating substantial interest in extending its capabilities in functional imaging applications such as blood perfusion and cardiac function. However, imaging cardiac structure and function in mice is challenging due to their small size and rapid heart rate. To overcome these challenges, we propose and compare improvements on two strategies for c...

The aim of this study was to compare three different cone-beam CT (CBCT) instruments used in dental clinical practice with micro-CT as gold standard. Three female monkeys' (Macaca fascicularis) skulls were selected and scanned by the tested CBCT-s. The most apical visible root canal level on the CBCT images was used as reference level (RL). After the image acquisition by CBCT-s dental jaw secti...

Front cover: Cover image: Reconstruction of the internal structures and mandibular arch a blackbelly lanternshark, Etmopterus lucifer based on micro-CT images. See M.A. Staggl colleagues, 'Head anatomy lantern shark wet-collection specimen (Chondrichthyes: Etmopteridae)', this issue.

This study aimed to evaluate the cause-effect relationship between canal preparation with ProTaper Universal (PTU) system and dentinal defects formation using micro-computed tomography (micro-CT) analysis. Forty mesial canals of mandibular molars with a type II Vertucci's canal configuration were scanned at an isotropic resolution of 14.16 µm. The sample was assigned to an experimental (n = 30)...

In x-ray micro-CT applications, it is useful to increase the field of view by offsetting a two-dimensional (2D) detector array. In this technical note, we briefly review the methods for image reconstruction with an asymmetric 2D detector array, elaborate on the use of an associated weighting scheme in the case of helical/spiral cone-beam scanning, and perform a series of numerical tests to demo...

A method for sharpening of 3D volume images has been developed. The idea of the proposed algorithm is to transform the 3D neighborhood of the edge so that the neighboring pixels move closer to the edge, and then resample the image from the warped grid to the original pixel grid. The proposed technique preserves image textures while making the edges sharper. The effectiveness of the proposed met...