UNLABELLED SPECT has the potential to add valuable information to the diagnosis and management of central nervous system (CNS) malignancy. Radioactive tracers including (99m)Tc-methoxyisobutylisonitrile (MIBI), or sestamibi, have been shown to be sensitive markers for brain tumors; however, their role in imaging children is poorly defined. METHODS We undertook a pilot study of 29 pairs of (99...

We use the Hill function to analyze the dynamics of Tc-99m 2 methoxy-isobutyl-isonitrile (Tc-MIBI) scintigraphy data and to examine the earlier lower extremity microvascular perfusion of diabetic patients without typical clinical symptoms and with the preserved normal ankle-brachial index (ABI).Eighty-eight participants (30 healthy control, 34 diabetic patients, and 24 diabetic patients with pe...

Evaluating the Effect of Injected Dose 99mTc- MIBI on Quantitative Parameters Myocardial Perfusion Imaging

Background: proper assessment of patients with ischemic cardiomyopathy is a key determinant for management other investigations, improving the patient’s quality life and reducing future cardiac events. This study was conducted to evaluate value myocardial MIBI washout rate using delayed resting perfusion imaging in limited resources countries. Patients Methods: this prospective included 86 (64 ...

AIM Hepatobiliary scintigraphy is an integral part in the diagnostic work-up of the neonatal cholestasis syndrome. However, less than optimal specificity is its major disadvantage. Differentiation between biliary atresia and neonatal hepatitis is nearly impossible in some cases with poor hepatocellular function. 99mTc sestamibi (MIBI) is a cationic lipophilic agent which is a substrate of P-gly...

Technetium 99m-hexakis-2-methoxy-2-methylpropyl-isonitrile (Tc-MIBI) is a promising new myocardial perfusion imaging agent producing excellent rest images. Imaging, however, will need to be performed with exercise or dipyridamole to detect ischemia and to differentiate salvaged but still ischemic myocardium from scar. Accordingly, 12 dogs were given mild-to-moderate left circumflex coronary ste...

Objective: Technetium-99m-sestamibi (-1"'Tc-MIBI) is a radiopharmaceutical imaging agent useful for assessing myocardial perfusion. We present a simple, rapid and accurate SepPak® method to confirm the radiochemical purity of "'Tc-MIBI. Methods: Technetium-99m-MIBI preparations of high (>95%), intermediate (83-90%) and low (25-43%) radiochemical purity were evaluated by the recommended thinlaye...

We aimed to evaluate the diagnostic and preoperative localization capacity of 99mTc methoxyisobutylnitrile (MIBI) parathyroid scintigraphy and ultrasonography (USG) in enlarged parathyroid glands in the primary hyperparathyroidism (pHPT) as well as the relationship between the success rate of these techniques and biochemical values. In this study, we retrospectively evaluated 39 patients with c...

OBJECTIVE In this study, we aimed to evaluate the diagnostic value of Technetium-99m methoxyisobutylisonitrile (Tc-99m MIBI) gated myocardial perfusion SPECT (MPS) in the detection of coronary artery disease (CAD) and silent myocardial ischemia (SMI) in patients with asymptomatic type 2 diabetes mellitus (DM). MATERIALS AND METHODS For this purpose, 35 patients with type 2 DM and 15 volunteer...

The Mental Illness Beliefs Inventory (MIBI) measures the extent to which an individual subscribes to the medical model of mental illness. This paper reports the results of two preliminary validation studies. The first study establishes the initial psychometric properties for the MIBI, based on a sample of 222 students in the helping professions; the second study tests the model established in t...