Drosophila mutants provide an ideal model to study channel-type specificity of ion channel regulation in situ. In this study, the effects of divalent cations on voltage-gated K+ currents were investigated in acutely dissociated central neurons of Drosophila third instar larvae using the whole-cell patch-clamp recording. Our data showed that micromolar Cd2+ enhanced the peak inactivating current...

In a previous paper [Gould, East, Froud, McWhirter, Stefanova & Lee (1986) Biochem. J. 237, 217-227] we presented a kinetic model for the activity of the Ca2+ + Mg2+-activated ATPase of sarcoplasmic reticulum. Here we extend the model to account for the effects on ATPase activity of Mg2+, cations and anions. We find that Mg2+ concentrations in the millimolar range inhibit ATPase activity, which...

Polymyxin B interacts with divalent cations by displacing cations from their binding sites in the lipopolysaccharide (LPS) molecules. It leads to the disorganization of the outer membrane component of the Gram negative bacteria, which releases LPS component from bacterial surface causing severe membrane leakage and finally cell death. In this paper, the reversible activity of PMB was investigat...

Revealing the binding properties of calcium ion (Ca2+) and magnesium (Mg2+) to terrestrial chromophoric dissolved organic matter (CDOM) facilities understanding effect natural water components on photophysics matter. Steady-state time-resolved fluorescence spectrometry, dynamic light scattering were applied investigate quenching process CDOM by Ca2+ Mg2+. Due a remarkable decrease steady-state ...

In this study, highly ordered mesoporous silica material (SBA-15) functionalized with Diethyl 2 - (9 -fluorenyl) malonate as a flourophore is reported. The anchoring of flourophores to the hydroxyl group on SBA-15 surface was done with post synthesis method. The obtained materials were characterized by small and wide angle X-ray diffraction, N2 adsorption–desorption, Fourier transform infrared ...

Lithium, declared critical raw material by the European Union in 2020, is a competitor to hydrogen as alternative petroleum. Its use increasing while reserves are declining, boosting new sources, seawater desalination concentrates. In this work, computational study of most promising extractants, β-diketones and organophosphates combinations thereof, towards lithium presence metal ions found con...

Salmonella typhimurium has three distinct Mg2+ transport systems, the constitutive high-capacity CorA transporter and two P-type ATPases, MgtA and MgtB, whose transcription is repressed by normal concentrations of Mg2+ in the growth medium. The latter Mg(2+)-transporting ATPase is part of a two-gene operon, mgtCB, with mgtC encoding a 23 kDa protein of unknown function. Transcriptional regulati...

Citrate transport in Bacillus subtilis is dependent on the presence of Mgz+. Other divalent cations like MnZ+, Co2+, or Ni2+ can replace magnesium ions. 2*Mg2+ or j4Mn2+ are taken up by the cells simultaneously with the uptake of citrate. Cells which are not induced for citrate transport do not show the citrate-dependent uptake of either 64Mn2+ or 2sMg2+. Citrate transport and the citrate-depen...

Despite the potential environmental benefits, use of membranes for extracting, reclaiming, and purifying alkali metals from aqueous feedstocks remains challenging due to low inter-cation selectivity. Two-dimensional materials equipped with nanoscale pores have revealed intriguing performance in ion separation, but their practical implementation is bottlenecked by perforation procedures. This wo...