The CCR4-NOT complex is a highly conserved, multifunctional machinery with a general role in controlling mRNA metabolism. It has been implicated in a number of different aspects of mRNA and protein expression, including mRNA degradation, transcription initiation and elongation, ubiquitination, and protein modification. The core CCR4-NOT complex is evolutionarily conserved and consists of at lea...

The ubiquitin-proteasome system regulates protein degradation in every eukaryotic cell. Recent work has shown that protein turnover mediated by the ubiquitin-proteasome system plays a key role in synaptic plasticity.

In this study the application of ZnO nanoparticles to UV photocatalytic degradation of nonionic surfactantTriton X-100 in aqueous media was investigated. The affecting factors on the photodegradation such as TritonX-100 initial concentration, nanocatalyst weight, pH, temperature and other parameters were studied anddescribed in details. The degradation rate was found to be strongly influenced b...

environmental degradation model is one of the environmental impact assessment (eia) methods in which ecological cumulative effects of human activities on his surrounding nature could be evaluated and quantified. as a special trait of landscape ecological metrics is the ability of rapid assess and recognize of human activities in the shortest time. thus in this study, we used a landscape degrada...

in this study, the degradation potential of five polycyclic aromatic hydrocarbons (pahs) by aerobic mixed bacterial cultures was investigated. microorganisms were isolated from hydrocarbon contaminated soils of shadegan wetland located in southwest of iran. the degradation experiments were conducted in liquid cultures. pah or pahs concentration was 100 mg/l at the beginning of degradation exper...

In this study, the ultrasonic, photocatalytic and sonophotocatalytic degradation of organics in textile industrial effluent was studied using ZnO nano catalyst, ZnO nano catalyst was synthesized by using sol-gel method. The structure and morphology of the catalyst were investigated using scanning election microscopy (SEM), electron dispersive X-ray spectroscopy (EDS) and X-ray <span id="transma...

fluvoxamine maleate is a selective serotonin reuptake inhibitor, which is used for the treatment of different types of depressive disorders. in the present study, a stability indicating hplc method was developed and validated for the determination of fluvoxamine maleate. the chromatographic separation was carried out using a nova-pak cn column and a mixture of k2hpo4 50 mm (ph 7.0) and acetonit...

conclusions according to the results, cop is an efficient and rapid method for removing of toluene from aqueous solutions. results the analysis of variance (anova) of the toluene degradation by cop/mgo nanoparticles showed f-value of 19.53 for the quadratic model indicating that the prepared model is significant. the predicted result showed that maximum degradation of toluene (~99.99%) could be...

continuous and excessive use of organophosphorus compounds has led to thecontamination of water and soil ecosystems. the degradation of organophosphorusinsecticides, chlorpyrifos, chlorpyrifos- methyl, cyanophos and malathion in mineral saltsmedia were studied. the effect of additional biofertilizers, singly or combined withorganic amendments, on chlorpyrifos and cyanophos degrading activity in...