BACKGROUND Ascorbic acid is an essential vitamin and a powerful antioxidant. Many studies have highlighted the benefits of ascorbic acid for chronic cardiovascular diseases such as hypertension in which angiotensin II (Ang II) plays an significant role. We therefore hypothesized that ascorbic acid could modify the pharmacological properties of the AT(1) receptor for Ang II. METHODS Binding st...

this study was designed to explore the protective effects of ascorbic acid and water extract of spirulina platensis (blue green algae) on methotrexate-induced lipid peroxidation using goat liver as the lipid source. this in vitro evaluation was done by measuring the malondialdehyde, 4-hydroxy-2-nonenal, reduced glutathione and nitric oxide content of tissue homogenates. the study reveals the li...

The aim of this study was to compare and analyze the site-specific accuracy of mixture of lipiodol and methylene blue (MLM) (0.6 ml, 1:5) and pure methylene blue (0.5 ml) on the rabbit lungs. In this study, CT-guided percutaneous injection of MLM and methylene blue. Compare the staining degree by biopsy of lung tissue. Use 4 points system to evaluate the site-specific accuracy at 6h and 24 h af...

22. MICHAELIS, L. Bio'ogical oxidations and reductions. Ann. Rev. Biochem. 16: 1-34. 1947. 23. POWERS, W. H., LEWIS, S., and DAWSON, C. R. The properties and preparation of a highly purified ascorbic acid oxidase. Jour. Gen. Physiol. 27: 167-180. 1944. 24. STEINMAN, H. G. and DAWSON, C. R. On the mechanism of the ascorbic acid-ascorbic acid oxidase reaction. The hydrogen peroxide question. Jour...

Diastereomeric ratios of >95 : 5 were obtained when performing methylene transfers onto imines originating from d-mannitol and (S)-(-)-2-methyl-2-propane sulfinamide or ascorbic acid and (R)-(-)-2-methyl-2-propane sulfinamide.

Introduction: Erythrocytes are highly specialized and the most abundant cell type in vertebrates’ blood. Their main function is the transportation of oxygen to tissues of the body via hemoglobin. Methods: The study was aimed at evaluating erythrocyte morphology in Clarias gariepinus (Cg), Bufo bufo (Bb), and Agama agama (Aa) using different stains; Also, morphometric analysis of erythrocyte w...

Abstract Numerous adsorbents have been introduced to efficiently remove heavy metals and organic dyes from environmental water samples. However, magnetic a porous network aerogels are rarely developed capture inorganic pollutants aqueous. We herein fabricated hexagonal boron nitride nanosheets ( h -BNNSs)-based on hybrid (MHAs) as lightweight adsorbent for robust uptake of Cr(VI), As(V), methyl...

We examined the effects of L-ascorbic acid and its analogues on DNA synthesis and cell proliferation. We also investigated the signal transduction pathways involved in the induction of mitogenesis by L-ascorbic acid and its analogues using primary cultures of adult rat hepatocytes. Following a 4-h serum-free cultivation, both L-ascorbic acid and its stable analogue, L-ascorbic acid 2-glucoside,...

to compare three various methods in the diagnosis of dentinal cracks formed in the apical third after root resection.one hundred extracted human maxillary central incisors were selected. the root canals were prepared with step-back technique. then 3mm from the apical end of all roots was cut perpendicular to the long axis of the tooth. the apical end of each root was evaluated to make sure ther...

introduction methylene blue was first described for the treatment of methemoglobinemia but practical usage of the compound for surgical purpose is common. the aim of this report is to describe a case of hemolysis in neonatal period as a potential hazard of methylene blue toxicity without presence of g6pd deficiency. case presentation in october 2015, a 36-week ga female infant with 2.05 kg weig...