Previous studies in our laboratory have been concerned with the pathway of carbon in the formation of methyl groups in photosynthesizing plants. In the biosynthesis of the N-methyl group of nicotine in tobacco plants, it was shown that, of several possible precursors, formaldehyde was incorporated to the greatest extent (1). This finding led to the suggestion that a “l-carbon” unit at the oxida...

The ability of attractants and repellents to affect the turnover of methyl groups on the methyl-accepting chemotaxis proteins (MCPs) was examined for Bacillus subtilis. Attractants were found to cause an increase in the turnover of methyl groups esterified to the MCPs, while repellents caused a decrease. These reactions do not require CheW. However, a cheW null mutant exhibits enhanced turnover...

The methyl groups of choline which have been shown to be donated in various reactions in animal metabolism (1, 2) have not been demonstrated to participate in plant methylation reactions. Experiments by Matchett, Kirkwood, and Marion (3, 4), Dubeck and Kirkwood (5), and Sribney and Kirkwood (6), with Hordeum distichum, Ricinus communis, and Dice&a hybrids in which choline was supplied as a poss...

Methionine is the main source of methyl groups that are partitioned to synthesize various methylated products including creatine, phosphatidylcholine (PC), and methylated DNA. Whether increased methylation of 1 product can divert methionine from protein synthesis or other methylation products was the aim of this experiment. We used an excess of guanidinoacetate (GAA) to synthesize creatine to c...

The aim of the present study was to determine the anti depressive activity of raw, autoclaved, boiled, germinated and roasted pumpkin seeds powder extract compared with the standard drug: Imipriamine (30 mg/kg) in normal and depressed control rats. Methyl Isobutyl Ketone (100 mg/kg) was used as the depression inducer in rats. The result shows that there was a significant (P < 0.01) decrease in ...

UNLABELLED Balance of labile methyl groups (choline, methionine, betaine, and folate) is important for normal liver function. Quantitatively, a significant use of labile methyl groups is in the production of phosphatidylcholines (PCs), which are ligands for the nuclear liver receptor homolog-1 (LRH-1). We studied the role of LRH-1 in methyl-pool homeostasis and determined its metabolic effects ...

Monodeuterated methyl groups may support a long-lived nuclear spin state, with a relaxation time exceeding the conventional spin-lattice relaxation time T1. Dissolution-DNP (dynamic nuclear polarization) may be used to hyperpolarize such a long-lived spin state. This is demonstrated for the CH2D groups of a piperidine derivative. The polarized sample is manipulated in the ambient magnetic field...

When 'mercury' is released into the environment it may appear as, or be converted into, any of the following chemical forms: metallic mercury (Hg) inorganic mercury (Hg + and Hg *) monomethyl mercury (CH3 Hg+) dimethyl mercury (CH3 Hg CH3) The 'methyl mercury' discussed in this appendix is monomethyl mercury (CH3 Hg+) 1. Man (a) Adult (i) Occupational exposure lab personnel industrial workers a...

in this work, the effect of ligand&apos;s length on interaction energy of six oximes, a [2-(hydroxyimino)-n-((1-(2-(2-((hydroxyimino)methyl)-1h-imidazol-1-yl)ethyl)-1h-1,2,3-triazol-4-yl)methyl)acetamide], b [2-(hydroxyimino)-n-((1-(3-(2-((hydroxyimino)methyl)-1h-imidazol-1-yl)propyl)-1h-1,2,3-triazol-4-yl)methyl)acetamide], c [2-(hydroxyimino)-n-((1-(4-(2-((hydroxyimino)methyl)-1h-imidazol-1-y...

We have studied the orientation of the train segments of a poly(methyl methacrylate) (PMMA) adsorbed layer at the CCl4-sapphire interface using surface-sensitive IR-visible sum frequency generation (SFG) spectroscopy. The SFG spectra of PMMA chains adsorbed on sapphire indicate ordered ester methyl groups. In comparison, we did not observe any significant contributions from the backbone methyle...