We report a clinical scenario involving 51-year-old male patient with history of prediabetes and gastritis who exhibited altered mental status following the consumption poppers, supplement containing nitrites, which is used for erectile stimulation. Shortly after ingestion, experienced convulsions, foaming at mouth, subsequently developed severe respiratory distress. The diagnosis methemoglobin...

The article presents experimental data on the effectiveness of drugs that could stimulate start metabolic adaptation during development methemoglobinemia. modeling this type hemic hypoxia led to disruption antioxidant protection, resulting in a rather significant decrease superoxide dismutase and catalase (primary enzymes) blood plasma tested animals. We have established anti-hypoxic activity w...

Acute-onset unexplained hypoxemia persisting despite 100% oxygen has a limited differential diagnosis but poses challenging diagnostic dilemma. Methemoglobinemia, hemolytic condition, may lead to significant complications if it goes undiagnosed during the critical golden hour of an emergency department (ED) presentation. This case report presents clinical details 30-month-old child with acute i...

I would like to add to this well written article that we have also reported acquired methemoglobinemia cases with administration of cytanest in puerperal women with g6PD deficiency and infants in whom erythrocyte cytochrome 65 reductase was assoyed [1-4], which is the main enzyme for methemoglobin reductase in erythrocytes as mentioned by the authors. In addition, hereditary methemoglobinemias ...

Background: Phenazopyridine is often prescribed for patients suffering from urinary tract infections as its local analgesic properties can provide immediate symptomatic improvement. It is classically taken for two days while awaiting antibiotic effect. It is available without a prescription in the United States under the trade names: Azo Urinary Pain Relief, Uricalm, and Uristat. Common adverse...

INTRODUCTION Methemoglobinemia should be considered in all cyanotic patients who remain unresponsive to oxygen therapy. Rapid diagnosis is very important in emergency cases. Here, we present the cases of two patients, a married couple, admitted to our hospital with methemoglobinemia after exposure to sodium nitrite. CASE PRESENTATION Two patients, a married couple, presented with methemoglobi...

congenital methemoglobinemia is a rare cause of cyanosis. we report a case of a girl, 17 years old with peripheral cyanosis and normal cardio-pulmonary system. she was diagnosed as a case of methemoglobinemia based on findings of polycythemia and hbm band on hemoglobin electrophoresis. we emphasize the importance of this rare entity in the differential diagnosis of cyanosis.