ABNORMAL BLOOD PIGMENTS CLEMENT A. FINCH, M.D. , AND JOSEPH F. ROSS, M.D. THE BLOOD PIGMENTS; THE PROPERTIES AND QUANTITATIVE DETERMINATION WITH SPECIAL REFERENCE TO THE SPECTROPHOTOMETRIC METHODS. H. 0. Michel andJ. S. Harris. J. Lab. & Clin. Med., a;.445-463, 1940. The authors present an orientational discussion of the nature and chemical properties of the various blood pigments derived from ...

OBJECTIVE To report two cases of methemoglobinemia induced by inhaled nitrobenzene and dermally absorbed aniline. METHODS We have evaluated a 37-year-old male worker exposed to nitrobenzene by inhalation while conducting maintenance job of mononitrobenzene pump and a 25-year-old male worker exposed dermally to aniline while unloading. RESULTS The first case is a 37-year-old male exposed to ...

A 9 month-old girl was given subcutaneous isosulfan blue to outline lymphatic channels during surgery for thoracic duct ligation. Her pulse oximetry values rapidly declined to a nadir of 85%, 35 min after dye injection. Arterial blood gases revealed methemoglobinemia ([MetHb] = 6.5%). Although abnormal pulse oximetry has already been reported in association with isosulfan blue, methemoglobinemi...

The reduction of hemoglobins (Hb) M such as Hb M Iwate, Hb M Boston, Hb M Hyde Park, Hb M Saskatoon, and Hb M Milwaukee by the ferredoxin and ferredoxin-NADP reductase system was studied systematically under anaerobic conditions. The enzyme system could not reduce the abnormal chains in methemoglobin M with an alpha chain anomaly but effectively converted the methemoglobin M with a beta chain a...

The in vitro behavior of various states of hemoglobin was examined over a wide range of concentrations. Solutions of increasing concentrations of oxyhemoglobin displayed significant increases in T1 and T2 relaxation rates that were insensitive to pH values between 6.0 and 6.9. Bovine serum albumin, which displayed a relaxation behavior nearly identical to that of oxyhemoglobin, was used to norm...

1. Pneumococci in contact with hemoglobin transform this into methemoglobin. This reaction occurs only when the pneumococci are living; it is not induced by the culture fluid or by extracts of the bacteria. 2. The reaction does not occur when hemoglobin is added to an emulsion of washed pneumococci in salt solution. However, if minute traces of dextrose be added to such a mixture, the reaction ...

INDIAN PEDIATRICS 1060 VOLUME 42__OCTOBER 17, 2005 electrophoresis and G6PD assay was also normal. Methemoglobin assayed by spectroscopic method was 38% (normal <1%.). Erythrocyte NADH-dependent methemoglobin reductase level was low with 30% of normal. HbM could not be estimated due to financial constraint. She was managed with oxygen inhalation, bronchodilator nebulisation, and oral antibiotic...

Generation of superoxide and hydrogen peroxide during interaction of nitrite with human hemoglobin was detected by chemiluminescence of luminol. Luminol chemiluminescence was inhibited by the addition of superoxide dismutase (SOD) and catalase. Methemoglobin formation induced by nitrite was also inhibited by the addition of SOD and catalase. The mechanism of methemoglobin formation by nitrite w...