نتایج جستجو برای: metallothioneins

تعداد نتایج: 771  

Journal: :Acta Crystallographica Section A Foundations of Crystallography 2009

Journal: :Environmental Health Perspectives 1986

Journal: :Journal of molecular biology 1999
R Riek B Prêcheur Y Wang E A Mackay G Wider P Güntert A Liu J H Kägi K Wüthrich

The three-dimensional structure of [(113)Cd7]-metallothionein-A (MTA) of the sea urchin Strongylocentrotus purpuratus was determined by homonuclear(1)H NMR experiments and heteronuclear [(1)H, (113)Cd]-correlation spectroscopy. MTA is composed of two globular domains, an N-terminal four-metal domain of the amino acid residues 1 to 36 and a Cd4Cys11cluster, and a C-terminal three-metal domain in...

Journal: :Environmental Health Perspectives 1986
R W Olafson

Techniques have been developed for detection, quantitation, and isolation of bacterial metallothioneins (MTs) from cyanobacterial species. These methods involve differential pulse polarography and reverse-phase high-performance liquid chromatography (HPLC) and have allowed detection of picomole quantities of these high sulfhydryl content proteins. The prokaryotic molecule was found to be induce...

Journal: :Polish journal of pathology : official journal of the Polish Society of Pathologists 2004
Piotr Dziegiel

Metallothioneins (MT) are low molecular weight proteins present both in normal and in neoplastic cells. They represent the main mechanism of the cell which protects it from action of heavy metal ions and the principal zinc-binding proteins. MT act as controllers of zinc-dependent enzymes, participating, i.a., in cell proliferation processes. The latter is of basic significance also in neoplasti...

2017
Kavitha Subramanian Vignesh George S Deepe

Metallothioneins (MTs) are a family of metal-binding proteins virtually expressed in all organisms including prokaryotes, lower eukaryotes, invertebrates and mammals. These proteins regulate homeostasis of zinc (Zn) and copper (Cu), mitigate heavy metal poisoning, and alleviate superoxide stress. In recent years, MTs have emerged as an important, yet largely underappreciated, component of the i...

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