نتایج جستجو برای: metalloprotease

تعداد نتایج: 3114  

Journal: :The Journal of Cell Biology 1992
D Muir M Manthorpe

Our previous report (Muir, D., S. Varon, and M. Manthorpe. 1990. J. Cell Biol. 109:2663-2672) described the isolation and partial characterization of a 55-kD antiproliferative protein found in Schwann cell (SC) and schwannoma cell line-conditioned media and we concluded that SC proliferation is under negative autocrine control. In the present study the 55-kD protein was found to possess metallo...

Journal: :Japanese journal of infectious diseases 2005
Rui Kano Tsuyoshi Yamada Koichi Makimura Hideyo Yamaguchi Shinichi Watanabe Atsuhiko Hasegawa

The full-length cDNA sequence for metalloprotease (MEP) of Arthroderma gypseum (one of the teleomorphs of the Microsporum gypseum complex) was determined by the 5'-rapid amplification of cDNA ends (RACE) and 3'-RACE methods using cDNA as a template. The full-length cDNA sequence of the MEP (2,670 bp) gene was proved to encode 677 amino acids. The amino acid sequence of the A. gypseum MEP gene s...

2013
Pedro M. Quirós Andrew J. Ramsay Carlos López-Otín

The mitochondrial quality control system is essential for the preservation and regulation of mitochondrial function. This system is formed by a complex machinery that controls and maintains protein function and regulates mitochondrial morphology through a coordinated system of continual fusion and fission events. Impairments in the mitochondrial quality control system through either mutation or...

Journal: :Proceedings of the National Academy of Sciences 2006

Journal: :The Journal of biological chemistry 2011
Davide M Ferraris Diego Sbardella Agnese Petrera Stefano Marini Beat Amstutz Massimo Coletta Peter Sander Menico Rizzi

Mycobacterium tuberculosis, the causative agent of tuberculosis, parasitizes host macrophages. The resistance of the tubercle bacilli to the macrophage hostile environment relates to their ability to impair phagosome maturation and its fusion with the lysosome, thus preventing the formation of the phago-lysosome and eventually arresting the process of phagocytosis. The M. tuberculosis zinc-depe...

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