background: a high prevalence of human t-cell lymphotropic virus type 1 (htlv-1) infection among general population in the northeast of iran has been reported. multi-transfused patients are known as ‘at-risk’ group for the infection. this systematic review and meta-analysis was conducted to estimate the prevalence of htlv-1 infection among iranian multi-transfused patients. materials and method...

 abstract the present study aimed to determine the prevalence of hypothyroidism, hypoparathyroidism and the frequency of regular chelation therapy in patients with thalassemia major in iran. searching process was performed by two independent  researchers using valid keywords in the national and international database, including: magiran, iranmedex, sid, medlib, scopus, pubmed, science direct, ...

matrix metalloproteinases (mmps) play an important role in gastric cancer (gc). accumulated evidence suggests that functional mmp-1 and mmp-7 gene polymorphisms are associated with several tumors. the aim of this study was to investigate two single nucleotide polymorphisms, mmp-1 -1607 1g/2g and mmp-7 -181 a/g, and their potential relationship with gc. we examined 246 gc  patients and 252 age-a...

background: coffee is implicated in the susceptibility to several cancers. however, the association between coffee and lymphoma remains unclear. this meta-analysis aimed to assess quantitatively the association between coffee and the incidence of lymphoma. methods: a literature search was performed for cohort and case-control studies published using pubmed, cochrane, and embase databases. studi...

the association between β2-adrenergic receptor (adrb2) -16arg/gly polymorphism (rs1042713) and chronic obstructive pulmonary disease (copd) risk has been investigated in many published studies. however, the results were inconclusive. a meta-analysis was performed to make a more precise estimation of the relationship.the pubmed, embase, isi web of science, the cochrane database of systematic rev...

objective herpes simplex virus (hsv), one of the most common sexually transmitted disease is a worldwide .this study aimed to prevalence of herpes simplex virus of pregnancy in iran. methods: we searched pubmed, scopus, ovid, science direct and national databases were searched: magiran, iranmedex and science information database (sid) up to october 2015.eventually, we included five studies that...

background : peptic ulcer is common and symptoms such as epigastria pain and heartburn, the results of various studies and aim of study was to evaluate the prevalence of gastric ulcers in the systematic review and meta-analysis is a method. materials and methods : 6 iranian papers in the range of 2002 to 2012 are selected using valid keywords in the sid, goggle scholar and elsevier databases an...

introduction: there are various studies looking at the effects of formocresol (fc) and mineral trioxide aggregate (mta) on pulpotomy of primary molars. this is a systematic review of literature comparing the success rates of mta and fc in pulpotomy of primary molars. materials and methods: the study list was obtained using pubmed, embase, scopus, science citation index, iran medex, google schol...

background: chronic obstructive pulmonary disease (copd) is usually considered one of the leading causes of death worldwide, so finding proper therapeutic strategies for this disease is of high importance. in this meta-analysis, we reviewed the existing literature on the efficacy and safety of conventional long acting beta agonists (labas) in copd patients. methods: we searched medline and goog...

background: intravenous immunoglobulin (ivig) is an established treatment of immune mediated demyelinating neuropathy including guillain-barré syndrome and chronic inflammatory demyelinating polyneuropathy. recent trials suggest its efficacy in treating relapsing- remitting multiple sclerosis. ivig exerts a number of effects, which may be beneficial in treating multiple sclerosis (ms): reductio...