Malignant pleural mesothelioma (MM) is a rare tumour with high mortality, which can exhibit various morphologies classified as epithelioid, biphasic and sarcomatoid subtypes. To investigate the molecular changes in these tumours, we studied gene expression patterns by combined use of cDNA arrays and tumour tissue microarrays (TMA). Deregulation of the expression of 588 cancer-related genes was ...

It has been established that coronary vessels develop through self-assembly of mesenchymal vascular progenitors in the subepicardium. Mesenchymal precursors of vascular smooth muscle cells and fibroblasts are known to originate from an epithelial-to-mesenchymal transformation of the epicardial mesothelium, but the origin of the coronary endothelium is still obscure. We herein report that at lea...

Accessible online at: www.karger.com/journals/res Involvement of the pleural mesothelium in inflammatory disease processes results in the development of an exudative pleural effusion. When the pleura itself is not inflamed and there is increased intravascular pressure, transudative effusions occur. This important concept is clearly illustrated in the paper by Alexandrakis and Bouros [1] in this...

•Incidental finding of a fallopian tube lesion at the time of bilateral salpingectomy•Histopathological appearance not consistent with mucinous or serous carcinoma, appearance of mesothelioma•Very rare known primary neoplasm of tubal mesothelium, favours an indolent course•Recommendation for prophylactic hysterectomy and bilateral oophorectomy•If nil further spread, generally nil further treatm...

The mortality from peritonitis is still high, so the question of pathogenesis this disease remains relevant. Of considerable interest are reactive and compensatory-adaptive changes in liver tissues during development peritonitis, since both general state body postoperative period depend on liver. purpose study was mesothelial cells serous membrane conditions acute experimental laboratory mice. ...