This study was designed to investigate the effect of inorganic mercury (mercuric chloride) on biochemical, hematological parameters, and examining the histological changes in liver, and kidney tissues in male albino mice as a laboratory animal Model. The animals used for the sub-chronic study for mercuric chloride received 1/100 , 1/50, 1/20 and 1/10 of the calculated LD50 which were equivalent...

Two chelating agents meso-2,3-dimercaptosuccinic acid (DMSA) and sodium 2,3-dimercapto-propane-1-sulphonate (DMPS) were tested for their efficiency in mercury removal from the body of rats in the presence and in the absence of selenium. Female Wistar rats were given a single intraperitoneal injection of mercuric chloride or an equimolar mixture of mercuric chloride and sodium selenite (1.5 micr...

abstract mercury compounds are widely used in several industries. such compounds can find their way to the environment causing its pollution. mercury is considered as a powerful carcinogenic agent. on the other side, the garlic extract is characterized by having compounds of specific anticarcinogenic action. therefore, the present study was conducted to investigate both the genotoxicity and cyt...

We investigated the effects of Heterodera glycines cyst components and surface disinfestants on hatching of H. glycines eggs in vitro. Eggs were incubated in either H. glycines cyst wall fragments, cyst wall and egg rinsate, egg homogenate, or control solutions of soybean root diffusate, sterile distilled water, or zinc sulfate. Hatch in cyst wall and egg rinsate, and egg homogenate, was greate...

Mercury has a long history as an antimicrobial agent effective against eukaryotic and prokaryotic organisms. Despite its prolonged use, the basis for mercury toxicity in prokaryotes is not well understood. Archaea, like bacteria, are prokaryotes but they use a simplified version of the eukaryotic transcription apparatus. This study examined the mechanism of mercury toxicity to the archaeal prok...

Survival of freezing not only requires organisms to tolerate ice formation within their body, but also depends on the rapid redistribution of water and cryoprotective compounds between intra- and extracellular compartments. Aquaporins are transmembrane proteins that serve as the major pathway through which water and small uncharged solutes (e.g. glycerol) enter and leave the cell. Consequently,...

Mercury (II) is a highly toxic metal which induced oxidative stress in the living organism. In the present study we examined the effect of S-Allyl cysteine (SAC) against the mercuric chloride (Hgcl2) intoxicated in albino rat model. The animals were treated with sub-leathal dose of mercuric chloride (1.23 mg/kg body wt) for 7 days. After scheduled treatetment the animals were decapitated and wh...

The primary aim of the present study was to evaluate the effects of different means of depleting glutathione (GSH) in the kidneys and liver on the renal and hepatic accumulation and disposition of a nontoxic dose of inorganic mercury. Renal and hepatic disposition of mercury were evaluated 1 hr after the intravenous administration of a 0.5 mumol/kg dose of mercuric chloride in control rats and ...

The present study investigates the influence of methanolic fraction (MF) of Tribulus terrestris fruit extract on the kidney tissues of mercury intoxicated mice, Mus musculus. At median-lethal dose of mercuric chloride (12.9 mg/kg body weight), the whole kidney tissue showed an increased level of lipid peroxidation (LPO), glutathione peroxidase (GPx) activities and simultaneously a decreased lev...