The objective of this study was to determine the time course of the plasma levels of meperidine administered by various routes. Ten healthy adults received 0.8 mg/kg of meperidine given intravenous, submucosal, intramuscular, and 1.4 mg/kg orally in a randomized sequence at a minimum of one-week intervals. Blood samples were collected at 0, 10, 20, 30, 45, 60, 90, 120, 180, 240, 360, and 720 mi...

BACKGROUND The ideal sedative agent for endoscopic procedures should allow a rapid modification of the sedation level and should not have any adverse effects. AIM To evaluate and compare the efficacy, safety, cost and patient satisfaction of some propofol-based sedation regimens administered during colonoscopy. MATERIAL AND METHODS One hundred twenty one patients scheduled for elective outp...

Vahabi S1, Ghafarzade M2, Lorzade N2, Moradkhani MR1, Frazan B1, Geranghadr P3 1. Assistant professor, Department of anesthesiology, Faculty of medicine, Lorestan University of medical sciences 2. Assistant professor, Department of gynecology, Faculty of medicine, Lorestan University of medical sciences 3. General practitioner Abstract Background: Postoperative nausea, vomiting (P...

Background: Shiveringis a common complication following anesthesia. Many drugs have been documented as prophylaxis of postanesthesia shivering. The aim this study was to find out better drug an antishivering agent.
 Materials and methods: This comparative carried in the Department Anesthesiology Chittagong Medical College Hospital over period 6 months starting from November 2015 April 2016...

conclusions midazolam/meperidine and propofol sedation for colonoscopy have similar cardiopulmonary safety profiles and patient satisfaction levels. midazolam/meperidine can be preferred to propofol sedation due to a shorter hospital length of stay and better analgesic activity. the patient satisfaction rates were not significantly different between the groups; however, patients in the propofol...

PURPOSE Remifentanil is a new, short-acting opioid that is similar pharmacodynamically to currently available opioids but differs in its pharmacokinetics. In the present study, we compared the use of remifentanil with the use of meperidine during intravenous conscious sedation for third molar surgery. PATIENTS AND METHODS Forty patients who were scheduled for the removal of impacted third mol...

background: strabismus surgery under general anesthesia is one of the most common ophthalmic procedures in children with emergence delirium as an important post-operative complication. additionally, postoperative pain is another important issue which is considered as a contributing factor to emergence delirium. we conducted a study to compare meperidine with paracetamol on postoperative pain an...

Education and operational changes and restrictions led to a sustained reduction in meperidine use.

BACKGROUND AND PURPOSE Therapeutic hypothermia shows promise as a treatment for acute stroke. Surface cooling techniques are being developed but, although noninvasive, they typically achieve slower cooling rates than endovascular methods. We assessed the hypothesis that the addition of intravenous MgSO4 to an antishivering pharmacological regimen increases the cooling rate when using a surface ...

Letter to the Editor regarding meperidine prescriptions in Queensland, Australia, 1999 to 2010.