Neuropsychological studies in electrical injury patients have reported deficits in attention, learning, and working memory, but the neural substrates of these deficits remain poorly characterized. In this study we sought to examine whether electrical injury subjects demonstrate abnormal patterns of brain activation during working memory and procedural learning tasks. Fourteen electrical injury ...

Previous studies have established that prospective memory is commonly affected following traumatic brain injury (TBI). This study examines whether demographic factors, injury severity and site, executive function, and metacognitive factors predict prospective memory performance in adults with TBI, using a cross-sectional multivariate correlational model. Prospective memory of 44 adults (mean ag...

Recent studies have focused on the role of N-methyl-d-aspartate (NMDA) in brain injury. The present study is aimed at verifying memory, anxiety/depression parameters, and cellular viability in the brain of mice preconditioned with NMDA and subjected to the model of mild traumatic brain injury. For this purpose, male albino CF-1 mice were pre-treated with NMDA (75 mg/kg) and subjected to brain t...

SEE BIGLER DOI101093/AWW277 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: Post-traumatic amnesia is very common immediately after traumatic brain injury. It is characterized by a confused, agitated state and a pronounced inability to encode new memories and sustain attention. Clinically, post-traumatic amnesia is an important predictor of functional outcome. However, despite its prevalence and f...

A 53-year-old male with history of traumatic brain injury (TBI) presented localized dissociative amnesia following a second head injury. While memory loss due to TBI is present in the literature, presentations this type are very rare. Although fully independent activities daily living, patient demonstrated severe deficits visual and processing speed upon neurocognitive evaluation. Effort testin...

The incidence of traumatic brain injury (TBI) among military personnel is at its highest point in U.S. history. Experimental animal models of blast have provided a wealth of insight into blast injury. The mechanisms of neurotrauma caused by blast, however, are still under debate. Specifically, it is unclear whether the blast shockwave in the absence of head motion is sufficient to induce brain ...

This study compares the rate of postconcussive (PCS) symptoms at the time of injury for mild traumatic brain injury (MTBI; N=24) claimants and claimants reporting other forms of injury (OI; N=66). On checklists surveying their complaints immediately after their injury, MTBI and OI claimants reported similar levels of many PCS complaints, e.g., dazed, confused, dizzy, disoriented, trouble concen...

Little is known about brain injury in concomitant mild traumatic brain injury (TBI) following traumatic spinal cord injury (TSCI). In this study, we reported on a male patient with memory impairment who showed injury of the Papez circuit following TSCI and concomitant mild TBI. A 59-year-old male underwent posterolateral fusion on T11–L2 due to an L1 burst fracture after falling from a height o...

We recently reported on three young patients with severe impairments of episodic memory resulting from brain injury sustained early in life. These findings have led us to hypothesize that such impairments might be a previously unrecognized consequence of perinatal hypoxic-ischaemic injury. Neuropsychological and quantitative magnetic resonance investigations were carried out on five young patie...

Penetrating traumatic brain injury (pTBI) is associated with deficits in cognitive tasks including comprehension and memory, and also with impairments in tasks of daily living. In naturalistic settings, one important component of cognitive task performance is event segmentation, the ability to parse the ongoing stream of behavior into meaningful units. Event segmentation ability is associated w...