Abstract Detection and isolation of target cells from heterogeneous mixtures are highly demanded in medicine, tissue engineering, cell biology. Likewise requested measuring techniques for significant biomarkers indicating changes cellular phenotype like size distribution deformability blood cells. A forward‐looking label‐free enrichment concept based on a membrane system made out stimulus‐respo...

Abstract Mitochondria are essential cellular organelles, which supply eukaryotic cells with the universal energy carrier adenosine triphosphate. These organelles feature a unique double-membrane architecture, is formed by smooth outer membrane and highly folded inner membrane. Harnessing super-resolution light electron microscopy, we investigate role of MICOS, large mitochondrial protein comple...

introduction: electroporation is a practical technique used to transport the molecules across the cell membrane. the utilization of fluorescent molecules is the method widely used to evaluate the electropermeability of cell membrane as a result of pulse application. it is also possible to use mathematical methods to predict the changes caused in cell electropermeability as a result of the chang...

Abstract Cell membrane vesicles, as delivery carriers of drugs or biological agents in vivo, are an important therapeutic mode the study disease treatment. Tumor membrane-derived vesicles have been widely used tumor therapy because their good enrichment effect. The most common method is surface nanoparticles coated with cell membrane, which can effectively prolong circulation time particles blo...

objective: endothelium is a selective and permeable membrane for transferring nutrients and vital components to arterial wall. endothelial damage might lead to altered biological function of endothelium and clinical consequences such as atherosclerosis. blood pressure pulse always exerts circumferential tension to the arterial wall. hence, such tension together with other loads, play important ...

auto-reactive cells-mediated immune responses are responsible for the current tissue damages during autoimmunity. accordingly, functional modulation of auto-reactive cells has been a pivotal aim in many of recent studies. in the current study, we investigated the possibility for insertion of regulatory molecules onto auto-reactive cells through exosomal nano-shuttles as a novel approach for phe...

Objective: The objective of the present study was to evaluate the cytotoxic potentials of Evolvulus alsinoides in human hepatoma HepG2 cells. Materials and Methods: HepG2 cells were treated with methanolic extract of E. alsinoides at 20, 40 and 80 µg/ml for 24 hr and cytotoxic effect was analyzed by MTT assay. The apoptosis rate was investigated by Hoechst 33342 and annexin V/propidium iodide s...

conclusions our results suggested that cb-nk cells progenitors could proliferate and differentiate on feeder layer of amnion membrane mscs in combination with specific cytokines to produce nk cells for immunotherapy. results combination of cytokines and msc layer yielded significant fold expansion in comparison with cytokines without feeder conditions (day 7: 5.2 ± 1.12 and 2 ± 0.78, respective...

hedera helix  is widely used to treat bronchial asthma for many years. however, effects of this herb on lung histopathology is still far from clear. we aimed to determine the effect of oral administration of hedera helix on lung histopathology in a murine model of chronic asthma. balb/c  mice  were  divided  into  four  groups;   i  (placebo),  ii  (hedera  helix), iii (dexamethasone) and iv (c...