Anxiety is feeling of danger in a person who is threatening with something. Nowadays, anxiety is increased in different populations and, thus it is became an important problem in many countries. Melissa officinalis (Melissa) and Valeriana officinalis (Valerian) are two medicinal plants. These two plants are traditionally used as sedative herbal drugs and new studies on their pharmacological act...

BACKGROUND Several studies are conducted on Premenstrual Syndrome (PMS). However, a few herbal surveys exist on the treatment of PMS in Iran. Due to the sedative effects of Melissa officinalis (M. officinalis), this question comes to mind that "can it be used in the treatment of PMS symptoms?" OBJECTIVES The current study aimed to assess the effect of M. officinalis capsule on the intensity o...

Lemon balm (Melissa officinalis L.) has many biological effects but especially important is its neuroprotective activity. The aim of the study is to produce different extracts of Melissa officinalis and analyse their chemical composition and biological properties on rat glioblastoma C6 cells. Results revealed that rosmarinic acid (RA) is the predominant compound of lemon balm extracts. RA has c...

OBJECTIVE Spinal cord injury (SCI) causes inflammation, deformity and cell loss. It has been shown that Melissa officinalis (MO), as herbal medicine, and dexamethasone (DEX) are useful in the prevention of various neurological diseases. The present study evaluated combinational effects of DEX and MO on spinal cord injury. MATERIALS AND METHODS Thirty six adult male Wistar rats were used in th...

This study was designed to determine chemical composition and antibacterial activity of essential oil from Melissa officinalis leaves. The essential oil was obtained by hydro-distillation and analyzed by gas chromatography-mass spectrometry (GC-MS). Antibacterial activity was evaluated by micro-dilution and disk-diffusion methods. The GC-MS analysis of the essential oil revealed 48 compounds in...

Melissa officinalis L. (Lamiaceae) had been reported in traditional Moroccan medicine to exhibit calming, antispasmodic, and strengthening heart effects. Therefore, this study is aimed at determining the anti-inflammatory activities of M. officinalis L. leaves. The effect of the essential oil of the leaves of this plant was investigated for anti-inflammatory properties by using carrageenan and ...