Phytochemical investigation on the stems of C. tabularis (Meliaceae) led to the isolation of two new phragmalin-type limonoids, named tabularisins S and T (1-2), along with five known ones (3-7). The structures of the new limonoids were established by spectroscopic methods including UV, IR, HRESIMS, and 1D and 2D NMR. All the compounds were evaluated for α-glucosidase inhibitory activity in vit...

Rohitukine, a chromane alkaloid, is a precursor of flavopiridol, a promising anti-cancer compound. Currently in Phase III clinical trials, flavopiridol is a potent inhibitor of several cyclin-dependent kinases (CDKs). Rohitukine was first reported from Amoora rohituka (0.083% dry weight) followed by that in Dysoxylum binectariferum (0.9% dry weight), both belonging to the family Meliaceae. Here...

The aerial parts and seeds of Swietenia macrophylla King (Meliaceae) are used in exotic medicine systems. In the present study, a preliminary phytochemical and few pharmacological profiles were under taken. The physical constans, extractive and ash values were examined. The presence of secondary metabolites in the aerial parts and seeds showed that Swietenia macrophylla is a good source of acti...

Natural products, including plants, animals and minerals have been the basis of treatment of human diseases. Melia azedarach L, commonly known as mahanimba belongs to family Meliaceae. It is large evergreen tree found throughout India and very similar to neem. Traditionally it is used as anthelmintic, antilithic diuretic, astringent and stomachic [1]. Various scientific studies reported the ant...

Pollen analysis of a sediment sample obtained at 222 cm from the top of a drilling core collected in the Bay of Guanabara, Rio de Janeiro, was used as a tool to obtain more knowledge about pre-historical human living and environment. 14C datation revealed the age of 4210 years B.P. Most frequent pollen grains came from plants like Alchornea (Euphorbiaceae), Celtis (Ulmaceae), Lecythidaceae, Mel...

Macrophomina phaseolina (Tassi) Goid is a soil-borne fungal pathogen that causes root rot disease in more than 500 plant species but no registered fungicide is available for its control. The present study was carried out to investigate the antifungal activity of aqueous leaf extracts of Azadirachta indica A. Juss., Melia azedarach L. and Toona ciliata Roxb. (Meliaceae) against M. phaseolina. Aq...

Dalbergia sissoo and Azadirachta indica are commonly known trees of India. They belong to family leguminoseae (fabaceae) and meliaceae respectively. They are broadly used in folk medicine for several diseases. The present study is carried out on biochemical parameters i.e. on content of protein and glycogen with standardized method in liver and kidney of Sprague-dawley rats. Due to combined ext...

Swietenia mahagoni Jacq. commonly known as West Indian Mahogany belongs to the family Meliaceae and is a valuable tree of commercial and ethno pharmacological importance. The present review aims to compile the scattered information regarding the morphological features, chemical constituents and medicinal importance of the plant. The different parts of S. mahagoni Jacq. (Leaves, bark, fruits) ar...