Bermudagrass [Cynodon dactylon (L.) Pers.] is a perennial grass and has been long used as a medicinal herb in Iranian traditional medicine to treat varied ailments. Different parts of bermudagrass such as leaves, stolons, rhizomes and culms are rich sources of metabolites such as proteins, carbohydrates, mineral constituents, β-sitosterol, flavonoids, alkaloids, glycosides and triterpenoides. G...

Background & Aim: The world production and consumption of essential oils and perfumes are increasing very fast. Lippia citriodora H.B.K. is an herbal species mainly used as a spice and medicinal plant. Endogenous levels as well exogenous application of plant growth regulators (PGR) could affect essential oil production and chemical compositions. Experimental: To study the effect of ex...

In 1997, the human corneal epithelium was reconstructed in vitro and transplanted on patients. Later, it became a routine treatment, before regulations considered advanced therapy medicinal products and drugs on the same lines. Manufacturing, before and after good manufacturing practice setting, was established in different facilities and the clinical application in several hospitals. Advanced ...

Plants have been used as a source of medicine since historic times and several commercially important drugs are of plant-based origin. The traditional approach towards discovery of plant-based drugs often times involves significant amount of time and expenditure. These labor-intensive approaches have struggled to keep pace with the rapid development of high-throughput technologies. In the era o...

The inherited culture of the uses of medicinal plants by local inhabitants were documented in Wadi El-Gemal National Park, Eastern Desert, Egypt. A total of 70 plant species were recorded as sources of medicines. The inhabitants are currently using only 32 plant species for treating various diseases. About 40.2% of the recorded uses were for treating digestive tract disorders, 13.4% for nervous...

Recent years have seen a dramatic increase in the amount and availability of data in the diverse areas of medicinal chemistry, making it possible to achieve significant advances in fields such as the design, synthesis and biological evaluation of compounds. However, with this data explosion, the storage, management and analysis of available data to extract relevant information has become even a...

Status Last revised May 1993 Previous titles/other references Biostatistical methodology in clinical trials in applications for Marketing Authorisations for Medicinal Products/ III/3630/92, Additional Notes This note for guidance concerns the application of Part 4, sections C and F of the Annex to Directive 75/318/EEC as amended with a view to the granting of a marketing authorisation for a med...