BACKGROUND The goal of this study was to determine if exposure to meconium would alter the phenotype of amniotic fluid mesenchymal stem cells (AF-MSCs) and the ability of these cells to be differentiated into distal airway type cells. METHODS Meconium was collected, lyophilized and resuspended in PBS at 3 different concentrations (high, medium, and low). AF-MSCs were cultured in the presence ...

Two antigens cross-reactive with carc inoembryonic antigen (CEA) and distinct from the nonspecif ic cross-react ing antigen were identified in meconium by double immunodiffusion with a conventional goat ant i -CEA antiserum. These two antigens together competi t ively inhibited cross-react ing antibodies against them in CEA radioimmunoassay and contr ibuted to the measurement of meconium CEA le...

During a 4-year routine screening programme for cystic fibrosis (CF) 15 464 specimens were examined for raised meconium albumin levels by a test strip method and by electroimmunoassay. The incidence of false-positive results was about 5 per 1000 specimens in either test. This could be reduced by 90% by determining the ratio of albumin : alpha-1-trypsin inhibitor (a ratio below 2.0 being conside...

Table II in the article shows thin meconium in trachea in 51.9% of the cases, whereas Table III shows thin meconium in trachea in 54.8% of the cases! Table IV shows that out of 9 babies who had intrapartum suctioning alone only one baby developed Meconium Aspiration Syndrome (MAS) (11.1%), while of those who received both intrapartum suctioning and endotracheal suctioning, 16.1% developed MAS t...

Bull, F. E., Gladwin, D. E. O., and Griffiths, A. D. (1974). Archives ofDisease in Childhood, 49, 602. Immunochemical method for detection of albumin in human meconium. A simple immunochemical technique utilizing single radial immunodiffusion for the demonstration of albumin in human meconium is described. A comparison of this technique with the more widely used sulphosalicylic acid precipitati...

Meconium from babies with cystic fibrosis (CF) has been shown by Green and Shwachman (1968) to contain readily detectable amounts of albumin. Screening for the disease is therefore possible by testing meconium specimens for the presence of albumin with albustix or Boehringer test tape. Any screening procedure, however, requires the availability of reliable methods for checking positive and doub...

Background: The presence of meconium-stained amniotic fluid (MSAF) is believed to be one the surest signs fetal distress in utero due hypoxia. objective study determine maternal factors, mode delivery and perinatal outcome for liquor.Methods: A prospective observational 500 women with term pregnancy having liquor during labour after spontaneous or artificial rupture membranes from 01 October 20...

OBJECTIVE To test the hypothesis that total liquid ventilation enables a more effective and better tolerated lavage than a bronchoalveolar lavage performed with diluted surfactant in a newborn ovine model of severe acute meconium aspiration syndrome. DESIGN Prospective, randomized, interventional study. SETTING Animal research laboratory at the Faculté de médecine et des sciences de la sant...

BACKGROUND There is little evidence linking meconium stained liquor to poor perinatal outcome and clear amniotic fluid is frequently considered a reassuring sign during labour. OBJECTIVE To determine whether there are any differences in cardiotocography (CTG) tracings and perinatal outcomes in women with meconium stained compared with those with clear liquor in labour. DESIGN A prospective ...