The aim of this study was to assess the clinical efficacy and safety of mechanically assisted thrombolysis in the treatment of acute cerebral infarction. Mechanically assisted intra-arterial urokinase thrombolysis was conducted on 28 patients with acute cerebral infarction with a disease onset time of 90-450 min. The maximum level of urokinase was 1,150,000 units. Thrombus disruption with a mic...

Humans produce exhaled breath particles (EBPs) during various breath activities, such as normal breathing, coughing, talking, and sneezing. Airborne transmission risk exists when EBPs have attached pathogens. Until recently, few investigations had evaluated the size and concentration distributions of EBPs from mechanically ventilated patients with different ventilation mode settings. This study...

The origins of bronchoscopy date back to 1897 when Gustav Killian, considered “the father of bronchoscopy”, performed the first airway examination with a rigid esophagoscope to a farmer extracting a piece of bone that had lodged in the main stem bronchus. Shigeto Ikeda in 1964 revolutionized the field of bronchoscopy with the introduction of a flexible instrument that could be introduced to sub...

When a newly developed experimental method to vibrate vellus hairs on human skin was applied to the face and arm in healthy subjects, intense itch was reproducibly induced on the face, but not on the arm, without any flare reactions. In contrast to histamine-induced itch, mechanically evoked itch was not characterized as burning or stinging by any subjects, and was resistant to histamine H1-rec...

We report a tunable nanophotonic device concept based on flexible photonic crystal, which is comprised of a periodic array of high-index dielectric material and a low-index flexible polymer. Tunability is achieved by applying mechanical force with nano-/microelectromechanical system actuators. The mechanical stress induces changes in the periodicity of the photonic crystal and consequently modi...

Sensory mechanical transduction - necessary for hearing, proprioception, and the senses of touch and pain - remains poorly understood. In somatosensation, even the basic properties of the mechanically sensitive excitatory ionic currents that are assumed to mediate mechanical transduction are largely undescribed. We have recorded, from the soma of rat dorsal root ganglion (DRG) neurons in vitro,...

Mechanicky indukované premeny kremíka V práci sa študujú zmeny veľkosti častíc a štruktúry kremíka pri vibračnom a planetárnom mletí vo vzduchu a v kvapalinách rôznej permitivity (metanol, acetón a benzén). Kinetika redukcie veľkosti častíc a zmien štruktúry závisí od relatívneho zrýchlenia pohybu mlecích telies a od povahy mlecieho prostredia. Najefektívnejšie zjemnenie a ochrana povrchu prášk...

The synthesis of rotaxane-type species composed of pyrene macrocycles and SWNTs as linear components is described. Pyrene-SWNT interactions help template the ring-closing metathesis of U-shaped precursors around the nanotubes.

Calculational abstract interpretation, long advocated by Cousot, is a technique for deriving correct-by-construction abstract interpreters from the formal semantics of programming languages. This paper addresses the problem of deriving correct-by-verifiedconstruction abstract interpreters with the use of a proof assistant. We identify several technical challenges to overcome with the aim of sup...

Two donor-acceptor [3]catenanes-composed of a tetracationic molecular square, cyclobis(paraquat-4,4'-biphenylene), as the π-electron deficient ring and either two tetrathiafulvalene (TTF) and 1,5-dioxynaphthalene (DNP) containing macrocycles or two TTF-butadiyne-containing macrocycles as the π-electron rich components-have been investigated in order to study their ability to form TTF radical di...