Rubella is a viral disease with minor morbidity and few complication unless it is contracted by a pregnant woman. Rubella infection during the first trimester of pregnancy often leads to fetal death or severe congenital defects (congenital rubella syndrome, CRS). Rubella remains endemic in many countries of Latin America and the Caribbean. It has been estimated that 20,000 or more infants are p...

GOAL OF THE MEASLES AEROSOL VACCINE PROJECT .................................................................................. 1 WHY A MEASLES AEROSOL VACCINE? .......................................................................................................... 1 The potential to reduce the challenges link to injection safety and waste management ....................... 1 Positive lessons ...

AIM This study evaluated the immunogenicity and safety of tetravalent measles-mumps-rubella-varicella (MMRV) vaccine produced with measles and rubella monovalent bulks derived from a newly established working seed virus stock (MMRV(new WS)) compared with the combined MMRV vaccine derived from the current seed virus stock, in Taiwanese and Singaporean children (NCT00892775). METHODS Healthy ch...

Measles vaccine was introduced in Gipuzkoa (Basque country, Spain) in 1978 and was replaced by the measles, mumps, and rubella (MMR) vaccine for children aged 12-15 months in 1981. A second dose of the MMR vaccine was introduced in 1992. Both doses of the MMR vaccine were well accepted by the population and high coverage was achieved (95% and 91% for the first and second doses respectively for ...

Adults born between 1966 and 1980 are at higher risk of measles, mumps and rubella, due to relatively low levels of immunity. Adults born before 1966 have probably been exposed to wild virus, and those born since 1980 have probably received two doses of measles, mumps, rubella (MMR) vaccine. Those born between 1966 and 1980 may not have had two doses because of changes in the immunisation sched...

PURPOSE This study (NCT00751348) evaluated the immunogenicity and safety of a combined measles-mumps-rubella-varicella (MMRV) vaccine compared to co-administration of measles-mumps-rubella and varicella (MMR+V) vaccines in Korean children during their second year of life. MATERIALS AND METHODS Healthy children aged 11-24 months received one dose of MMRV or MMR+V. Antibody titers against measl...

BACKGROUND The combination measles-mumps-rubella-varicella (MMRV) vaccine currently used in Canada (Priorix-Tetra) may increase the risk of febrile seizures relative to the separate vaccines (MMR and varicella) previously administered. We determined the risk of febrile seizure after the first dose of MMRV, as well as any additional risk for children at high risk for seizures because of pre-exis...

The purpose of this study was to examine the efficacy rendered with a single dose of live attenuated measles, rubella, mumps, and varicella containing vaccine. We inoculated healthcare workers (HCWs) with a single dose of vaccine to a disease lacking in antibody titer for those not meeting the criteria of our hospital (measles: <16.0 (IgG enzyme immunoassay (EIA)), rubella: ≤1:32 (hemagglutinat...

Rubella is a highly contagious viral infection that can cause devastating effects on growing fetus. Although rubella be prevented with the measles, mumps and (MMR) vaccine, some individuals have weak immune response do not sustain an adequate antibody titer to protect against disease. MMR titers are routinely assessed in general population, although healthcare professionals, military workers pr...

Abstract Background Updated seroprevalence studies of infections in migrants may aid the design tailored vaccination and prevention programmes. The objective this study was to describe rates for potentially transmissible viral attended at a referral centre major European city. Methods Descriptive analysis vaccine-preventable non-vaccine-preventable Madrid, Spain (2018–19). Recorded variables in...