In an increasingly integrated world with declining trade barriers, environmental regulations can have a decisive role in shaping countries’ comparative advantages. The conventional wisdom about environmental protection is that it comes at an additional cost on firms imposed by the government, which may erode their global competitiveness. However, this paradigm has been challenged by some analys...

In this study, metal matrix composites (MMC) of a CoCrNi medium entropy alloy (MEA) reinforced with titanium nitride (TiN) nano-sized particles were designed for production by laser-based powder bed fusion (LB-PBF). Two different additions, 0.5 wt% and 5 TiN nano- sized particles, mixed using tumbling ball milling, respectively. The results suggest that although the morphology is not significan...

Epilepsy, affecting about 1% of the population, comprises a group of neurological disorders characterized by the periodic occurrence of seizures, which disrupt normal brain function. Despite treatment with currently available antiepileptic drugs targeting neuronal functions, one third of patients with epilepsy are pharmacoresistant. In this condition, surgical resection of the brain area genera...

BACKGROUND Bioavailable testosterone (BT) concentration is considered the best marker for evaluating testicular function in men. The decrease of BT in older men is more pronounced than the decrease in total testosterone because of the parallel increase in sex hormone-binding globulin (SHBG) concentrations. Measurement of BT is therefore crucial for the diagnosis of hypoandrogenism in the aging ...

Author Affiliations: Service de Médecine Interne, Centre Hospitalier National d’Ophtalmologie des QuinzeVingts, Paris, France (Drs Feldman-Billard and Héron); and Service d’Ophtalmologie (Dr Massin) and Service de Médecine Interne B (Drs Meas and Guillausseau), Hôpital Lariboisière, Université Paris VII, Assistance Publique-Hôpitaux de Paris, Paris. Correspondence: Dr Feldman-Billard, Service d...

Microelectrode arrays (MEAs) are appealing tools to probe large neural ensembles and build neural prostheses. Microelectronics microfabrication technologies now allow building high-density MEAs containing several hundreds of microelectrodes. However, several major problems become limiting factors when the size of the microelectrodes decreases. In particular, regarding recording of neural activi...