BACKGROUND Total food intake is a function of meal size and meal frequency, and adjustments to these parameters allow animals to maintain a stable energy balance in changing environmental conditions. The physiological mechanisms that regulate meal size have been studied in blowflies but have not been previously examined in Drosophila. RESULTS Here we show that mutations in the leucokinin neur...

BACKGROUND Ingestion of a meal stimulates colonic motility. It is unclear whether the nutrient composition of a meal affects colonic motor response. AIMS To investigate and compare the effects of a predominantly fat or carbohydrate meal on colonic motility. METHODS In 18 healthy subjects, ambulatory colonic manometry was performed by placing a six sensor, solid state probe from the mid-tran...

Several epidemiological studies have observed an inverse relationship between people's habitual frequency of eating and body weight, leading to the suggestion that a 'nibbling' meal pattern may help in the avoidance of obesity. A review of all pertinent studies shows that, although many fail to find any significant relationship, the relationship is consistently inverse in those that do observe ...

Background—Ingestion of a meal stimulates colonic motility. It is unclear whether the nutrient composition of a meal aVects colonic motor response. Aims—To investigate and compare the eVects of a predominantly fat or carbohydrate meal on colonic motility. Methods—In 18 healthy subjects, ambulatory colonic manometry was performed by placing a six sensor, solid state probe from the mid-transverse...

Early postnatal overnutrition results in a predisposition to develop obesity due in part to hypothalamic and sympathetic dysfunction. Potential involvement of another major regulatory system component--the vagus nerve--has not been examined. Moreover, feeding disturbances have rarely been investigated prior to development of obesity when confounds due to obesity are minimized. To examine these ...

OBJECTIVE We examined relationships of eating patterns and reported energy intake (rEI) with BMI percentile in U.S. children. RESEARCH METHODS AND PROCEDURES Two 24-hour dietary recalls from the Continuing Surveys of Food Intakes by Individuals 1994 to 1996 and 1998 (1005 boys, 990 girls) were averaged, and children were categorized into three age groups: 3 to 5 years (n = 1077), 6 to 11 year...

Several epidemiological studies have observed an inverse relationship between people’s habitual frequency of eating and body weight, leading to the suggestion that a ‘nibbling’ meal pattern may help in the avoidance of obesity. A review of all pertinent studies shows that, although many fail to find any significant relationship, the relationship is consistently inverse in those that do observe ...

The mechanisms by which OB protein controls food intake and energy balance are unknown. Therefore, we investigated the effects of a novel modified human recombinant OB protein (Mod-OB) on spontaneous feeding patterns, body weight, running wheel activity, and ovarian cycling in female rats. Mod-OB or vehicle was injected (4 mg ⋅ kg-1 ⋅ day-1sc) for 2 ovarian cycles (8 days) using a within-subjec...

INTRODUCTION During the last few decades, Egypt experienced rapid socio-cultural changes that were associated with major changes in the food choices and eating habits, which, progressively, becomes more westernized. The objective of this study was to investigate the meal patterns of secondary school adolescent students in Mansoura, Egypt. METHODS This is a cross-sectional study conducted on 8...