Affiliations: Tatiana Christides, Department of Life and Sports Science, Faculty of Engineering & Science, University of Greenwich, United Kingdom David Wray, Department of Pharmaceutical, Chemical & Environmental Sciences, Faculty of Engineering & Science, University of Greenwich, United Kingdom Richard McBride, Department of Life and Sports Science, Faculty of Engineering & Science, Universit...

Fragile X syndrome is the most common heritable cause of mental retardation. Previous work has suggested that overactive signaling by group I metabotropic glutamate receptors (mGluRs) may be a mechanism underlying many of the disease symptoms. As a test of this theory, McBride et al. show that in a Drosophila model for Fragile X syndrome, treatment with mGluR antagonists can rescue short-term m...

www.ums.ac.uk Dr Michael McBride is the new Chief Medical Officer (CMO) for Northern Ireland. A graduate of Queens University Belfast Medical School, he also trained in St Mary’s at Imperial College London. His specialist interest in HIV/AIDS suggested early on in his career that he was not afraid of working in a challenging and ever changing field. I met with him to discuss his vision of the N...

A new IIR adaptive notch filter (ANF) with fast convergence rate, accurate estimation of notch frequencies, and modest realization complexity is presented in this paper. The problem of obtaining a notch filter from a given signal containing multiple sine waves in noise is first formulated as the conventional problem of system identification. Then the new ANF is developed via the algorithm of St...

M. R. Gomez, R. M. Gilgenbach, M. E. Cuneo, C. A. Jennings, R. D. McBride, E. M. Waisman, B. T. Hutsel, W. A. Stygar, D. V. Rose, and Y. Maron Sandia National Laboratories, Albuquerque, New Mexico 87185, USA Nuclear Engineering and Radiological Sciences Department, University of Michigan, Ann Arbor, Michigan 48109, USA Voss Scientific, LLC, Albuquerque, New Mexico 87108, USA Department of Physi...

PAUL HANSMA (University of California, Santa Barbara): I have a question for Mike McBride. I was really interested in the data you showed (and you gave one number of 20 to 30 kilobars), because it kind of relates to the atomic force microscope. The question is, how hard can you push on a crystal before it deforms? Would it be possible to get from your data a graph of how hard you can push, in n...

The ITERATOR pattern gives a clean interface for element-by-element access to a collection. Imperative iterations using the pattern have two simultaneous aspects: mapping and accumulating. Various existing functional iterations model one or other of these, but not both simultaneously. We argue that McBride and Paterson’s idioms, and in particular the corresponding traverse operator, do exactly ...

In this paper, it is shown that induction is derivable in a type-assignment formulation of the second-order dependent type theory λP2, extended with the implicit product type of Miquel, dependent intersection type of Kopylov, and heterogeneous equality type of McBride. The crucial idea is to use dependent intersections to internalize a result of Leivant’s showing that Church-encoded data may be...

Abstract— In this paper, Recursive least square (RLS) based complex Adaptive notch filter (ANF) using Steiglitz-McBride (SM) method is proposed to suppress the Radio frequency interference (RFI) in very-highspeed digital subscriber line (VDSL) systems. The proposed RLS-SM ANF converges fast and requires less computational complexity than the existing direct form constrained ANF using recursive ...