Herein, we report the synthesis of 12 new naphthoquinone derivatives, 6 substituted 1,4-naphthoquinones and 6 heterocycle-fused naphthoquinones, as well as evaluation of their trypanocidal and leishmanicidal activities. Compounds 11a and 13a were active against the amastigote stage of T. cruzi and showed low cytotoxic effects. With respect to leishmanicidal assays, all compounds were inactive a...

CASE REPORT A 37–years old male patient of Indian origin was referred to the Department of Conservative Dentistry and Endodontics for treatment of carious teeth. An intraoral examination revealed an Angle’s Class I molar relation with a well aligned upper and a lower arch. Full complement of permanent teeth was present. Generalized dental fluorosis was seen in teeth of both arches. Though the t...

The vestibular system detects the velocity of the head even in complete darkness, and thus contributes to spatial orientation. However, during vestibular estimation of linear passive self-motion distance in darkness, healthy human subjects mainly rely on time, and they replicate also stimulus duration when required to reproduce previous self-rotation. We then made the hypothesis that the percep...

Let p ≡ 7 mod 16 be a prime. Then there are integers a, b, c, d with a ≡ 15 mod 16, b ≡ 0 mod 4, p = a + 2(b + c + d), and 2ab = c − 2cd − d. We show that there is a regular Hadamard matrix of order 4p provided that p = a± 2b or p = a+ δ1b+4δ2c+4δ1δ2d with δi = ±1. ∗This research was done during a visit of the first two authors at the University of Augsburg

The present experiments aimed at separating the impact stimulus and response predictions have on serial learning and performance in SRT tasks. In Experiment 1, a unique transition between two of four responses in an otherwise random response sequence was triggered by ambiguous stimulus transitions, allowing local response predictions but no stimulus predictions. The data indicated explicit tran...

A partial report procedure was used to test the ability of observers to split attention over noncontiguous locations. Observers reported the identity of 2 targets that appeared within a 5 x 5 stimulus array, and cues (validity = 80%) informed them of the 2 most likely target locations. On invalid trials, 1 of the targets appeared directly in between the cued locations. Experiments 1, 1a, and 2 ...

We prove the assertion in the title by conducting an exhaustive computational search for subgroups isomorphic to PSL2(13) and containing elements in class 13B.

Nucleophilic cycloaddition of thiocyanates 1a-e with C60 in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene afforded C60-fused 2-iminotetrahydrothiophene derivatives 2a-e and methanofullerenes 3a-d. The product distributions were highly sensitive to the substrates employed. The 2-iminotetrahydrothiophene derivatives 2a-e could be further manipulated by hydrolysis and acetylation to give 2-ox...

Cyclocondensation of 2-[bis(methylthio)methylene]malononitrile (1) and cysteamine (2) afforded 2-(thiazolidin-2-ylidene)malononitrile (3). This compound on treatment with NaSH gave the corresponding thioamide derivative 4a in a regioselective manner on the basis of its single crystal X-ray diffraction analysis. Reaction of this compound with several alpha-bromocarbonyl compounds gave new 2-(E)-...