نتایج جستجو برای: masterplan as mediator
تعداد نتایج: 5658071 فیلتر نتایج به سال:
Protein kinase B/Akt possesses prosurvival and antiapoptotic activities and is involved in growth factor-mediated neuronal protection. In this study we establish Akt deactivation as a causal mediator of cell death. Akt deactivation occurs in multiple models of cell death including N-methyl-d-aspartate excitotoxicity, vascular stroke, and nitric oxide (NO)- and hydrogen peroxide (H2O2)-elicited ...
Others have shown that yeast strains bearing a ts mutation in the Srb4 subunit of Mediator cease transcription of all mRNA at the restrictive temperature, in a manner virtually indistinguishable from a strain bearing a ts mutation in the largest subunit of RNA polymerase II. We find that srb4ts Mediator is defective for the stimulation of basal RNA polymerase II transcription at the restrictive...
Of the various hypotheses offered to explain atherosclerosis, inflammation now appears to provide a key to this pathological process. Inflammation has been shown to play a major role in precipitating a cascade of events from formation of the atheromatous lesion in response to vascular injury through lipid ingestion by macrophages, to subsequent rupture of the lesion, and myocardial infarction. ...
Current adaptation theory tends to consider individual buildings or the city level, which cannot address decisions related masterplan developments on large brownfield sites. This paper investigates drivers for building demolition retention and at scale. Expert interviews three case studies are used explore how why demolish, retain adapt, made this The research compared different geopolitical co...
This paper reports on the design process for Tokyo University of Science Katsushika Campus, which culminated in execution a masterplan, using urban planning, whereby campus was integrated with park. The result an park, making it model case planning future that characterized by liaison locality.
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