To examine a possible mechanism which could cause arterial hypoxaemia following pulmonary embolism, we collapsed and did not ventilate one lung in each of eleven dogs, to produce hypoxic pulmonary vasoconstriction. In five dogs (Starch Group), PaO2 fell from 10 to 7.7 kPa (76.6 to 58.4 torr) as shunt fraction (Qs/Qt) rose from 19 to 31 per cent. Mean pulmonary artery pressure (ppa), paCO2 and V...

THE ANTEMORTEM diagnosis of pulmonary arteriovenous fistula was made for the first time by Smith and Horton in 1939.1 The lesion was suspected from the appearance of the chest x-ray and subsequently proved by inj ection of contrast media into an arm vein with visualization of the abnormal vascular communication in the right lung. Since then many such lesions have been suspected from clinical fi...

THE ANTEMORTEM diagnosis of pulmonary arteriovenous fistula was made for the first time by Smith and Horton in 1939.1 The lesion was suspected from the appearance of the chest x-ray and subsequently proved by inj ection of contrast media into an arm vein with visualization of the abnormal vascular communication in the right lung. Since then many such lesions have been suspected from clinical fi...

HYLAND, JOHN W., GEORGE T. SMITH, LOCKHART B. MCGUIRE, DONALD C. HARRISON, FLORENCE W. HAYNES, AND LEWIS DEXTER. Efect of selective embolisation of various sized pulmonary arteries in dogs. Am. J. Physiol. 204(4) : 6 I g-625. I g63.-Pulmonary embolism was produced in 30 closed-chest 8-kg dogs with polystyrene spheres, glass beads, or blood clots of precise graded size. The sizes matched selecti...

Daptomycin has been used with success for the treatment of right-sided methicillin-resistant Staphylococcus aureus (MRSA) endocarditis. However, its efficacy has not been completely assessed for the treatment of MRSA endocarditis when it is associated with pulmonary septic emboli. Hereby, we present a case of MRSA mitral and tricuspid native valve endocarditis with pulmonary septic emboli, whic...

This case illustrates a rare but important differential diagnosis of pulmonary emboli in the field of thoracic oncology, that of pulmonary artery sarcoma. It describes particular clinical features that may raise suspicion of this tumor in cases of suspected pulmonary emboli, and highlights novel radiological modalities and tissue sampling techniques in such cases. Surgical resection, as part of...

pneumonia (CAP), including aspiration pneumonia, and a greater incidence of pulmonary tuberculosis compared with the general population. This relates to smoking, alcohol abuse, poor nutrition and homelessness. Organisms commonly causing CAP in this group include Streptococcus pneumoniae, S aureus, Haemophilus influenzae and Klebsiella pneumoniae.11,12 Septic pulmonary emboli can seed from injec...