Background: Estrogen deficiency can trigger several diseases, one of which is neurodegenerative. Neurodegenerative begins with neuroinflammation, triggers the activation microglia cells resulting in a pro-inflammatory activity. Potential and relatively safe therapy to use overcome it by using phytoestrogen compounds. Marsilea crenata Presl. plant that contains phytoestrogens. Objective: The pur...

Recent phylogenetic studies have provided compelling evidence that confirms the once disputed hypothesis of monophyly for heterosporous leptosporangiate ferns (Marsileaceae and Salviniaceae). Hypotheses for relationships among the three genera of Marsileaceae (Marsilea, Regnellidium, and Pilularia), however, have continued to be in conflict. The phylogeny of Marsileaceae is investigated here us...

Pendahuluan: Prevalensi penyakit neurodegeneratif meningkat tiap tahunnya dan mayoritas dialami perempuan yang mencapai fase menopause. Hal tersebut kemudian mengurangi kualitas hidup Penyakit pada wanita menopause sering diakibatkan oleh defisiensi estrogen, sehingga perlu adanya pengganti hormon estrogen dalam menjaga homeostasis sistem saraf pusat, salah satunya fitoestrogen. Salah satu tana...